Dr. Stefan Wilfried Rahlfs - Research portal of Justus Liebig University Giessen: - CRIS

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Dr. Stefan Wilfried Rahlfs

Email: stefan.rahlfs@ernaehrung.uni-giessen.de

Projects as principal investigator

SPP 1710 TP 2. Laufzeit - Das Glutathion-Redoxsystem als Thiol-Switch Operator in Plasmodium falciparum
01/06/2017 - 30/08/2020
German Research Foundation (DFG)
SPP 1710, TP, 1. Laufzeit - Das Glutathion-Redoxsystem als Thiol-Switch Operator in Plasmodium falciparum
21/02/2014 - 20/05/2017
German Research Foundation (DFG)

Projects as co-investigator or project member

Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase of the malaria parasite Plasmodium falciparum
01/02/2012 - 31/01/2015
German Research Foundation (DFG)

Publications

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Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase is a potential drug target (2015)
- The FEBS Journal
Allen, SM; Lim, EE; Jortzik, E; et al.
Journal article
Atomic resolution crystal structure of glutaredoxin 1 from Plasmodium falciparum and comparison with other glutaredoxins (2014)
- Acta Crystallographica. Section D: Biological Crystallography
Yogavel, M; Tripathi, T; Gupta, A; et al.
Journal article
Protein S-nitrosylation in Plasmodium falciparum (2014)
- Antioxidants & Redox Signaling
Wang, LH; Delahunty, C; Prieto, JH; et al.
Journal article
Redox Metabolism (2014)
Becker, Katja; Rahlfs, Stefan; Jortzik, Esther
Contribution in an anthology
Antiparasitic Peptides (2013)
- Advances in Biochemical Engineering Biotechnology
Pretzel, J; Mohring, F; Rahlfs, S; et al.
Contribution in an anthology
Characterization of tryptophan aminotransferase 1 of Malassezia furfur, the key enzyme in the production of indolic compounds by Malassezia furfur. (2013)
- Experimental Dermatology
Preuss, J; Hort, W; Lang, S; et al.
Journal article
Crystal Structure of the Plasmodium falciparum Thioredoxin Reductase-Thioredoxin Complex (2013)
- Journal of Molecular Biology
Fritz-Wolf, K; Jortzik, E; Stumpf, M; et al.
Journal article
Identification and Characterization of Novel Human Glucose-6-Phosphate Dehydrogenase Inhibitors (2013)
- Journal of Biomolecular Screening
Preuss, J; Richardson, AD; Pinkerton, A; et al.
Journal article
Real-Time Imaging of the Intracellular Glutathione Redox Potential in the Malaria Parasite Plasmodium falciparum (2013)
- PLoS Pathogens
Kasozi, D; Mohring, F; Rahlfs, S; et al.
Journal article
Analyzing Thiol-Dependent Redox Networks in the Presence of Methylene Blue and Other Antimalarial Agents with RT-PCR- Supported in silico Modeling (2012)
- Bioinformatics and Biology Insights
Zirkel, J; Cecil, A; Schäfer, F; et al.
Journal article
Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2 (2012)
- Molecular and Biochemical Parasitology
Zocher, K; Fritz-Wolf, K; Kehr, S; et al.
Journal article
Discovery of a Plasmodium falciparum Glucose-6-phosphate Dehydrogenase 6-phosphogluconolactonase Inhibitor (R,Z)-N-((1-Ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) That Reduces Parasite Growth in Vitro (2012)
- Journal of Medicinal Chemistry
Preuss, J; Maloney, P; Peddibhotla, S; et al.
Journal article
High-Throughput Screening for Small-Molecule Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase 6-Phosphogluconolactonase (2012)
- Journal of Biomolecular Screening
Preuss, J; Hedrick, M; Sergienko, E; et al.
Journal article
Insight into the Selenoproteome of the Malaria Parasite Plasmodium falciparum (2012)
- Antioxidants & Redox Signaling
Roseler, A; Prieto, JH; Iozef, R; et al.
Journal article
Subcellular localization of adenylate kinases in Plasmodium falciparum (2012)
- FEBS Letters
Ma, J; Rahlfs, S; Jortzik, E; et al.
Journal article