Uni.-Prof. Dr. Marek Bartkuhn
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ORCID: https://orcid.org/0000-0001-6872-9082 Researcher ID: GDF-8898-2022 |
Projects as principal investigator
- FOR 5644 INFINITE TP Z1 - Die Rolle von Immunzellen in der Funktion des normalen und pathologisch veränderten Hoden und Nebenhoden - Teilprojekt: Entschlüsselung der Funktion von Immunzellen in Hoden und Nebenhoden durch Einzelzelltranskriptomik, räumliche aufgelöste Proteomik und integrative Bioinformatik
01/08/2024 - 31/07/2028
German Research Foundation (DFG) - TRR 81 Z01 - Chromatin-Veränderungen in Differenzierung und Malignität - Teilprojekt: Bioinformatische Analyse genomweiter Datensätze
01/07/2010 - 30/06/2022
German Research Foundation (DFG)
Projects as co-investigator or project member
- Nukleosom-Präservierung in Säugetier-Spermien: ein epigenetisches Programm zur Wahrung der gesunden männlichen Reproduktion
01/01/2015 - 31/12/2020
German Research Foundation (DFG)
Publications
6 of 7
- The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner (2012)
- Epigenetics and Chromatin
Journal article - The relevance of acetylated histone H4 at lysine 12 (H4K12ac) for RNA transcripts in human spermatozoa, mouse pronucleus formation and parthenogenetic activation of murine oocytes (2012)
- European Urology Supplements
Meeting Abstract - Co-Localisation of two active epigenetic histone marks, H4K12ac and H3K9ac, in gene promoters of spermatozoa from fertile donors and subfertile patients (2011)
- European Urology Supplements
Meeting Abstract - Presence of histone H3 acetylated at lysine 9 in male germ cells and its distribution pattern in the genome of human spermatozoa (2011)
- Reproduction, Fertility and Development
Journal article - CTCF shapes chromatin by multiple mechanisms: the impact of 20 years of CTCF research on understanding the workings of chromatin (2010)
- Chromosoma
Journal article - Modular Insulators: Genome Wide Search for Composite CTCF/Thyroid Hormone Receptor Binding Sites (2010)
- PLoS ONE
Journal article - The accessibility of human sperm chromatin for H4K12ac-bindings is not limited by DNA methylation (2010)
- European Urology Supplements
Meeting Abstract - The interaction of modified histones with the bromodomain testis-specific (BRDT) gene and its mRNA level in sperm of fertile donors and subfertile men (2010)
- Reproduction
Journal article - Acetylated histone H4K12 exhibits different binding to sperm DNA between fertile men and infertile patients (2009)
- European Urology Supplements
Meeting Abstract - Active promoters and insulators are marked by the centrosomal protein 190 (2009)
- The EMBO Journal
Journal article - Colocalisation of different modified histones within BRDT gene locus of sperm DNA from fertile and infertile men (2009)
- European Urology Supplements
Meeting Abstract - Differential binding pattern of acetylated histone H4 at lysin 12 (H4K12ac) to the sperm DNA between healthy donors and infertile patients (2009)
- Journal of Andrology
Meeting Abstract - Long range chromatin interactions involved in gene regulation (2008)
- Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Journal article - CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex (2007)
- PLoS Genetics
Journal article - Hand is a direct target of the forkhead transcription factor Biniou during Drosophila visceral mesoderm differentiation (2007)
- BMC Developmental Biology
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