Uni.-Prof. Dr. Sandra B. Hake - Forschungsportal der Justus-Liebig-Universität Gießen: - FIS

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Uni.-Prof. Dr. Sandra B. Hake

ORCID: https://orcid.org/0000-0003-0029-6588

Projekte als Projektleitung

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Verständnis der funktionellen Rolle von ZNF512B in NuRD-abhängigen und -unabhängigen Chromatinprozessen
01.05.2024 - 30.04.2027
Deutsche Forschungsgemeinschaft (DFG)
Die funktionelle Rolle von HMG20A und dessen assoziierter Proteinkomplexe in der Regulation von Transkriptionsprogrammen in der Entwicklung
01.09.2023 - 31.08.2026
Deutsche Forschungsgemeinschaft (DFG)
Funktionelle und mechanistische Analyse des neuen H2A.Z-Bindeproteins MIER1
01.07.2022 - 30.09.2025
Deutsche Forschungsgemeinschaft (DFG)
Untersuchung zur evolutionären Transition der Nukleosomen Assemblierung
01.07.2022 - 30.09.2025
Deutsche Forschungsgemeinschaft (DFG)
Untersuchung der multivalenten Chromatin-Bindungseigenschaften von PWWP2A
18.07.2018 - 17.10.2021
Deutsche Forschungsgemeinschaft (DFG)

Publikationen

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PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex (2018)
- Nature Communications
Link, S; Spitzer, RMM; Sana, M; et al.
Journalartikel
H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements (2017)
- Nucleic Acids Research
Zink, LM; Delbarre, E; Eberl, HC; et al.
Journalartikel
Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation (2017)
- The EMBO Journal
Pünzeler, S; Link, S; Wagner, G; et al.
Journalartikel
PWWP2A: A novel mitosis link? (2017)
- Cell Cycle
Link, S; Hake, SB
Journalartikel
Variants of core histones and their roles in cell fate decisions, development and cancer. (2017)
- Nature Reviews Molecular Cell Biology
Buschbeck, M; Hake, SB
Journalartikel
Histone variant H2A.Z.2: A novel driver of melanoma progression (2016)
- Molecular & Cellular Oncology
Vardabasso, C; Hake, SB; Bernstein, E
Journalartikel
Histone variants: nuclear function and disease (2016)
- Current Opinion in Genetics & Development
Zink, LM; Hake, SB
Journalartikel
Histone Variant H2AZ2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma (2015)
- Molecular Cell
Vardabasso, C; Gaspar-Maia, A; Hasson, D; et al.
Journalartikel
The CENP-T C-terminus is exclusively proximal to H3.1 and not to H3.2 or H3.3. (2015)
- International Journal of Molecular Sciences
Abendroth, C; Hofmeister, A; Hake, SB; et al.
Journalartikel
Getting down to the core of histone modifications (2014)
- Chromosoma
Jack, AP; Hake, SB
Journalartikel
Histone glutamine methylation afFACTing rDNA transcription. (2014)
- Cell Research
Leonhardt, H; Hake, SB
Journalartikel
Structure-guided mutational analysis reveals the functional requirements for product specificity of DOT1 enzymes. (2014)
- Nature Communications
Dindar, G; Anger, AM; Mehlhorn, C; et al.
Journalartikel
The histone variant H2A.Bbd is enriched at sites of DNA synthesis (2014)
- Nucleic Acids Research
Sansoni, V; Casas-Delucchi, CS; Rajan, M; et al.
Journalartikel
H3K56me3 Is a Novel, Conserved Heterochromatic Mark That Largely but Not Completely Overlaps with H3K9me3 in Both Regulation and Localization (2013)
- PLoS ONE
Jack, APM; Bussemer, S; Hahn, M; et al.
Journalartikel
Histone h3 glutathionylation in proliferating mammalian cells destabilizes nucleosomal structure. (2013)
- Antioxidants & Redox Signaling
García-Giménez, JL; Òlaso, G; Hake, SB; et al.
Journalartikel