Journalartikel

Jahr der Veröffentlichung: 2009

Seiten: 1187-1198

Zeitschrift: Chemical Society Reviews

Bandnummer: 38

Heftnummer: 4

DOI Link: https://doi.org/10.1039/B801793J

Verlag: Royal Society of Chemistry

Abstract: 

The present critical review outlines the close relationship and
mutual interplay between molecular recognition, active site
considerations in enzyme catalysis involving anions, and organocatalysis
utilizing explicit hydrogen bonding. These interconnections are
generally not made although, as we demonstrate, they are quite apparent
as exemplified with pertinent examples in the field of (thio)urea
organocatalysis. Indeed, the concepts of anion binding or binding with
negatively (partially) charged heteroatoms is key for designing new
organocatalytic transformations. Utilizing anions through recognition
with hydrogen-bonding organocatalysts is still in its infancy but bears
great potential. In turn, the discovery and mechanistic elucidation of
such reactions is likely to improve the understanding of enzyme active
sites (108 references).

Harvard-Zitierstil: Zhang, Z. and Schreiner, P. (2009) (Thio)urea organocatalysis—What can be learnt from anion recognition?, Chemical Society Reviews, 38(4), pp. 1187-1198. https://doi.org/10.1039/B801793J

APA-Zitierstil: Zhang, Z., & Schreiner, P. (2009). (Thio)urea organocatalysis—What can be learnt from anion recognition?. Chemical Society Reviews. 38(4), 1187-1198. https://doi.org/10.1039/B801793J