Journalartikel

Thiourea-Catalyzed Transfer Hydrogenation of Aldimines


AutorenlisteZhang, Z; Schreiner, PR

Jahr der Veröffentlichung2007

Seiten988-988

ZeitschriftSYNFACTS: Highlights in Chemical Synthesis

Bandnummer2007

Heftnummer9

DOI Linkhttps://doi.org/10.1055/s-2007-968883

VerlagThieme Publishing / Georg Thieme Verlag


Abstract

The authors report a practical method for the reductive amination of
aldehydes and reduction of aldimines using thiourea catalyst 1
and also question some of the published results on the reductive
amination of aldehydes and ketones. They found that thiourea catalyst 2 is inefficient for the reductive amination of benz­aldehyde but thiourea catalyst 1 smoothly gave the product in 86% yield. In addition, with 1 mol% of catalyst 1, good to excellent yields (80-93%) were obtained for the reduction of different preformed aromatic and aliphatic aldimines.




Zitierstile

Harvard-ZitierstilZhang, Z. and Schreiner, P. (2007) Thiourea-Catalyzed Transfer Hydrogenation of Aldimines, Synfacts: Highlights in Current Synthetic Organic Chemistry, 2007(9), p. 988. https://doi.org/10.1055/s-2007-968883

APA-ZitierstilZhang, Z., & Schreiner, P. (2007). Thiourea-Catalyzed Transfer Hydrogenation of Aldimines. Synfacts: Highlights in Current Synthetic Organic Chemistry. 2007(9), 988. https://doi.org/10.1055/s-2007-968883


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