Journal article

Publication year: 2011

Pages: 49-54

Journal: RNA Biology

Volume number: 8

Issue number: 1

ISSN: 1547-6286

Open access status: Green

DOI Link: https://doi.org/10.4161/rna.8.1.14066

Publisher: Taylor and Francis Group

Abstract: 
The archaeal exosome is a prokaryotic protein complex with RNA processing and degrading activities. Recently it was shown that the exosome is localized at the periphery of the cell in the thermoacidophilic archaeon Sulfolobus solfataricus. This localization is most likely mediated by the archaeal DnaG protein and depends on (direct or indirect) hydrophobic interactions with the membrane. A localization of RNA degrading proteins and protein complexes was also demonstrated in several bacteria. In bacteria a subcellular localization was also shown for substrates of these proteins and protein complexes, i.e., chromosomally encoded mRNAs and a small RNA. Thus, despite the missing compart-mentalization, a spatial organization of RNA processing and degradation exists in prokaryotic cells. Recent data suggest that the spatial organization contributes to the temporal regulation of these processes.

Harvard Citation style: Evguenieva-Hackenberg, E., Roppelt, V., Lassek, C. and Klug, G. (2011) Subcellular localization of RNA degrading proteins and protein complexes in prokaryotes, RNA Biology, 8(1), pp. 49-54. https://doi.org/10.4161/rna.8.1.14066

APA Citation style: Evguenieva-Hackenberg, E., Roppelt, V., Lassek, C., & Klug, G. (2011). Subcellular localization of RNA degrading proteins and protein complexes in prokaryotes. RNA Biology. 8(1), 49-54. https://doi.org/10.4161/rna.8.1.14066