Journalartikel

Jahr der Veröffentlichung: 2011

Seiten: 3306-3313

Zeitschrift: Microbiology

Bandnummer: 157

ISSN: 1350-0872

DOI Link: https://doi.org/10.1099/mic.0.051607-0

Verlag: Microbiology Society

Abstract: 
Metal homeostasis is important in all living cells in order to provide sufficient amounts of metal ions for biological processes but to prevent toxic effects by excess amounts. Here we show that the gene product of RSP_2889 of the facultatively photosynthetic bacterium Rhodobacter sphaeroides is homologous to CueR, a regulator of copper metabolism in Escherichia coli and other bacteria. CueR binds to the promoter regions of genes for a copper-translocating ATPase and for a copper chaperone and is responsible for their high expression when cells are exposed to elevated levels of copper ions. While deletion of RSP_2889 has no significant effect on copper resistance, expression from a low-copy-number plasmid mediates increased sensitivity to copper.

Harvard-Zitierstil: Peuser, V., Glaeser, J. and Klug, G. (2011) The RSP_2889 gene product of Rhodobacter sphaeroides is a CueR homologue controlling copper-responsive genes, Microbiology, 157, pp. 3306-3313. https://doi.org/10.1099/mic.0.051607-0

APA-Zitierstil: Peuser, V., Glaeser, J., & Klug, G. (2011). The RSP_2889 gene product of Rhodobacter sphaeroides is a CueR homologue controlling copper-responsive genes. Microbiology. 157, 3306-3313. https://doi.org/10.1099/mic.0.051607-0