Journal article

Publication year: 2007

Pages: 226-232

Journal: Genes, Genomes and Genomics

Volume number: 1

Issue number: 2

URL: http://www.globalsciencebooks.info/Online/GSBOnline/images/0712/GGG_1(2)/GGG_1(2)226-232o.pdf

Publisher: Global Science Books

Abstract: 
Thioredoxins are small, ubiquitous proteins with a dithiol/disulfide active site (CGPC) and have been characterized in a wide variety of prokaryotic and eukaryotic cells. In the thioredoxin system, thioredoxin reductase serves to reversibly reduce oxidized thioredoxin using NAD(P)H as electron donor. In 1964, thioredoxin was originally discovered as electron donor for ribonucleotide reductase in Escherichia coli. By now, many thioredoxins are identified to fulfil a number of important cellular functions, e.g. they are the major cellular protein disulfide reductases, controlling the cellular redox potential. The multiple and important functions of thioredoxins necessitate to adjust their cellular levels according to the requirements. Despite the importance of thioredoxin functions, only little is known about the regulation of thioredoxin genes. The present review therefore considers bacterial genes encoding thioredoxins. We give an overview on thioredoxin genes and their regulation in different bacteria. Furthermore, we will review the current knowledge about the participation of thioredoxin proteins in the regulation of gene expression and protein activity.

Harvard Citation style: Zeller, T. and Klug, G. (2007) Bacterial thioredoxins - genes and regulation, Genes, Genomes and Genomics, 1(2), pp. 226-232. http://www.globalsciencebooks.info/Online/GSBOnline/images/0712/GGG_1(2)/GGG_1(2)226-232o.pdf

APA Citation style: Zeller, T., & Klug, G. (2007). Bacterial thioredoxins - genes and regulation. Genes, Genomes and Genomics. 1(2), 226-232. http://www.globalsciencebooks.info/Online/GSBOnline/images/0712/GGG_1(2)/GGG_1(2)226-232o.pdf