Journalartikel

Jahr der Veröffentlichung: 2005

Seiten: 7635-7639

Zeitschrift: Angewandte Chemie International Edition

Bandnummer: 44

Heftnummer: 46

ISSN: 1433-7851

DOI Link: https://doi.org/10.1002/anie.200502908

Verlag: Wiley

Abstract: 

Catching proteins: Proteins from a protein–DNA microarray can be directly detected by using MALDI mass spectrometry. Capture proteins are attached to silicon chips in a highly selective and reversible way by DNA‐directed immobilization (see picture). The analyte proteins bound specifically to their partners on the microarray can be detected from cell lysates. Catching proteins: Proteins from a protein–DNA microarray can be directly detected by using MALDI mass spectrometry. Capture proteins are attached to silicon chips in a highly selective and reversible way by DNA‐directed immobilization (see picture). The analyte proteins bound specifically to their partners on the microarray can be detected from cell lysates.

Harvard-Zitierstil: Becker, C., Wacker, R., Bouschen, W., Seidel, R., Kolaric, B., Lang, P., et al. (2005) Direct readout of protein-protein interactions by mass spectrometry from protein-DNA microarrays, Angewandte Chemie International Edition, 44(46), pp. 7635-7639. https://doi.org/10.1002/anie.200502908

APA-Zitierstil: Becker, C., Wacker, R., Bouschen, W., Seidel, R., Kolaric, B., Lang, P., Schroeder, H., Müller, O., Niemeyer, C., Spengler, B., Goody, R., & Engelhard, M. (2005). Direct readout of protein-protein interactions by mass spectrometry from protein-DNA microarrays. Angewandte Chemie International Edition. 44(46), 7635-7639. https://doi.org/10.1002/anie.200502908