Kinetic isotope effects for the C-H activation step in phase-transfer halogenations of alkanes - Forschungsportal der Justus-Liebig-Universität Gießen:

Journalartikel

Kinetic isotope effects for the C-H activation step in phase-transfer halogenations of alkanes

Autorenliste: Lauenstein, O; Fokin, AA; Schreiner, PR

Jahr der Veröffentlichung: 2000

Seiten: 2201-2204

Zeitschrift: Organic Letters

Bandnummer: 2

Heftnummer: 15

ISSN: 1523-7060

DOI Link: https://doi.org/10.1021/ol0059347

Verlag: American Chemical Society

Abstract:
Within the scope of phase-transfer halogenations (Br and I) of alkanes, significant HID kinetic isotope effects (KIE = 4-5) indicate that hydrogen abstraction is rate limiting. The excellent agreement of computed and experimentally determined H/D KIE as well as trapping experiments support the involvement of trihalomethyl radicals in the activation step.

Autoren/Herausgeber

- Uni.-Prof. Dr. Peter Richard Schreiner, PhD

Zitierstile

Harvard-Zitierstil: Lauenstein, O., Fokin, A. and Schreiner, P. (2000) Kinetic isotope effects for the C-H activation step in phase-transfer halogenations of alkanes, Organic Letters, 2(15), pp. 2201-2204. https://doi.org/10.1021/ol0059347

APA-Zitierstil: Lauenstein, O., Fokin, A., & Schreiner, P. (2000). Kinetic isotope effects for the C-H activation step in phase-transfer halogenations of alkanes. Organic Letters. 2(15), 2201-2204. https://doi.org/10.1021/ol0059347