Journal article

Organocatalytic alkynylation of aldehydes and ketones under phase-transfer catalytic conditions


Authors list: Weil, T; Schreiner, PR

Publication year: 2005

Pages: 2213-2217

Journal: European Journal of Organic Chemistry

Volume number: 2005

Issue number: 11

ISSN: 1434-193X

DOI Link: https://doi.org/10.1002/ejoc.200500064

Publisher: Wiley


Abstract: 
We developed alkynylations of various aldehydes and ketones under practical phase-transfer conditions at room temperature. The straightforward methodology combines one-pot synthesis and simple workup with good to excellent yields for propargylic alcohols derived from aliphatic aldehydes and ketones. Even aromatic aldehydes and ketones could be transformed to the corresponding propargylic alcohols in somewhat lower yields. The yield depending on the amount of PT catalyst and NaOH concentration was also determined.



Citation Styles

Harvard Citation style: Weil, T. and Schreiner, P. (2005) Organocatalytic alkynylation of aldehydes and ketones under phase-transfer catalytic conditions, European Journal of Organic Chemistry, 2005(11), pp. 2213-2217. https://doi.org/10.1002/ejoc.200500064

APA Citation style: Weil, T., & Schreiner, P. (2005). Organocatalytic alkynylation of aldehydes and ketones under phase-transfer catalytic conditions. European Journal of Organic Chemistry. 2005(11), 2213-2217. https://doi.org/10.1002/ejoc.200500064


Last updated on 2025-21-05 at 13:32