Journal article

Publication year: 2003

Pages: 419-430

Journal: Microbiology

Volume number: 149

Issue number: 2

ISSN: 1350-0872

Open access status: Bronze

DOI Link: https://doi.org/10.1099/mic.0.25978-0

Publisher: Microbiology Society

Abstract: 
Thioredoxins are small ubiquitous proteins that display different functions mainly via redox-mediated processes. The facultatively photosynthetic bacterium Rhodobacter capsulatus harbours at least two genes for thioredoxin 1 and 2, trxA and trxC. It is demonstrated that thioredoxin 2 of R. capsulatus can partially replace the thioredoxin 1 function as a hydrogen donor for methionine sulfoxide reductase but cannot replace thioredoxin 1 as a subunit of phage T7 DNA polymerase. By inactivating the trxC gene in R. capsulatus, it is shown that thioredoxin 2 is involved in resistance against oxidative stress. As thioredoxin 1 of Rhodobacter sphaeroides, R. capsulatus thioredoxin 2 affects the oxygen-dependent expression of photosynthesis genes, albeit in an opposite way. The trxC mutant of R. capsulatus shows a stronger increase in photosynthesis gene expression after a decrease in oxygen tension than the isogenic wild-type strain. The expression of the trxC gene is downregulated by oxygen.

Harvard Citation style: Li, K., Hartig, E. and Klug, G. (2003) Thioredoxin 2 is involved in oxidative stress defence and redox-dependent expression of photosynthesis genes in Rhodobacter capsulatus, Microbiology, 149(2), pp. 419-430. https://doi.org/10.1099/mic.0.25978-0

APA Citation style: Li, K., Hartig, E., & Klug, G. (2003). Thioredoxin 2 is involved in oxidative stress defence and redox-dependent expression of photosynthesis genes in Rhodobacter capsulatus. Microbiology. 149(2), 419-430. https://doi.org/10.1099/mic.0.25978-0