Journal article

Chromosome-encoded Ambler class A beta-lactamase of Kluyvera georgiana, a probable progenitor of a subgroup of CTX-M extended-spectrum beta-lactamases


Authors listPoirel, L; Kämpfer, P; Nordmann, P

Publication year2002

Pages4038-4040

JournalAntimicrobial Agents and Chemotherapy

Volume number46

Issue number12

ISSN0066-4804

eISSN1098-6596

Open access statusGreen

DOI Linkhttps://doi.org/10.1128/AAC.46.12.4038-4040.2002

PublisherAmerican Society for Microbiology


Abstract
A chromosome-encoded beta-lactamase gene, cloned and expressed in Escherichia coli from Kluyvera georgiana reference strain CUETM 4246-74 (DSM 9408), encoded the extended-spectrum beta-lactamase KLUG-1, which shared 99% amino acid identity with the plasmid-mediated beta-lactamase CTX-M-8. This work provides further evidence that Kluyvera spp. may be the progenitor(s) of CTX-M-type beta-lactamases.



Citation Styles

Harvard Citation stylePoirel, L., Kämpfer, P. and Nordmann, P. (2002) Chromosome-encoded Ambler class A beta-lactamase of Kluyvera georgiana, a probable progenitor of a subgroup of CTX-M extended-spectrum beta-lactamases, Antimicrobial Agents and Chemotherapy, 46(12), pp. 4038-4040. https://doi.org/10.1128/AAC.46.12.4038-4040.2002

APA Citation stylePoirel, L., Kämpfer, P., & Nordmann, P. (2002). Chromosome-encoded Ambler class A beta-lactamase of Kluyvera georgiana, a probable progenitor of a subgroup of CTX-M extended-spectrum beta-lactamases. Antimicrobial Agents and Chemotherapy. 46(12), 4038-4040. https://doi.org/10.1128/AAC.46.12.4038-4040.2002


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