Journalartikel

Jahr der Veröffentlichung: 2012

Seiten: 1724-1727

Zeitschrift: Organic Letters

Bandnummer: 14

Heftnummer: 7

ISSN: 1523-7060

DOI Link: https://doi.org/10.1021/ol300307c

Verlag: American Chemical Society

Abstract: 

Bordwell’s method of overlapping indicators was used to determine the pK_a
values of some of the most popular (thio)urea organocatalysts via UV
spectrophotometric titrations. The incremental effect of CF₃ groups on acidic strength was also investigated. The pK_a’s
are in the range of 8.5–19.6. The results may lead to a better
understanding of noncovalent organocatalysis and may aid in future
catalyst development.

Harvard-Zitierstil: Jakab, G., Tancon, C., Zhang, Z., Lippert, K. and Schreiner, P. (2012) (Thio)urea Organocatalyst Equilibrium Acidities in DMSO, Organic Letters, 14(7), pp. 1724-1727. https://doi.org/10.1021/ol300307c

APA-Zitierstil: Jakab, G., Tancon, C., Zhang, Z., Lippert, K., & Schreiner, P. (2012). (Thio)urea Organocatalyst Equilibrium Acidities in DMSO. Organic Letters. 14(7), 1724-1727. https://doi.org/10.1021/ol300307c