Contribution in an anthology

Endocannabinoid Modulation in the Olfactory Epithelium


Authors listBreunig, E; Czesnik, D; Piscitelli, F; Di Marzo, V; Manzini, I; Schild, D

Appeared inSensory and metabolic control of energy balance

Editor listMeyerhof, W; Beissiegel, U; Joost, HG

Publication year2010

Pages139-145

ISBN978-3-642-14425-7

eISBN978-3-642-14426-4

DOI Linkhttps://doi.org/10.1007/978-3-642-14426-4_11

Title of seriesResults and problems in cell differentiation

Number in series52


Abstract

Appetite, food intake, and energy balance are closely linked to the endocannabinoid system in the central nervous system. Now, endocannabinoid modulation has been discovered in the peripheral olfactory system of larval Xenopus laevis. The endocannabinoid 2-AG has been shown to influence odorant-detection thresholds according to the hunger state of the animal. Hungry animals have increased 2-AG levels due to enhanced synthesis of 2-AG in sustentacular supporting cells. This renders olfactory receptor neurons, exhibiting CB1 receptors, more sensitive at detecting lower odorant concentrations, which probably helps the animal to locate food. Since taste and vision are also influenced by endocannabinoids, this kind of modulation might boost sensory inputs of food in hungry animals.




Authors/Editors




Citation Styles

Harvard Citation styleBreunig, E., Czesnik, D., Piscitelli, F., Di Marzo, V., Manzini, I. and Schild, D. (2010) Endocannabinoid Modulation in the Olfactory Epithelium, in Meyerhof, W., Beissiegel, U. and Joost, H. (eds.) Sensory and metabolic control of energy balance. Berlin: Springer-Verlag, pp. 139-145. https://doi.org/10.1007/978-3-642-14426-4_11

APA Citation styleBreunig, E., Czesnik, D., Piscitelli, F., Di Marzo, V., Manzini, I., & Schild, D. (2010). Endocannabinoid Modulation in the Olfactory Epithelium. In Meyerhof, W., Beissiegel, U., & Joost, H. (Eds.), Sensory and metabolic control of energy balance (pp. 139-145). Springer-Verlag. https://doi.org/10.1007/978-3-642-14426-4_11


Last updated on 2025-21-05 at 15:01