Journal article

Publication year: 2003

Pages: 741-751

Journal: Anatomical Record

Volume number: 273A

Issue number: 2

DOI Link: https://doi.org/10.1002/ar.a.10082

Publisher: Wiley

Abstract: 

The purpose of the present study was to examine the process of bone
formation in the regenerating cranial appendages of roe deer (Capreolus capreolus) and fallow deer (Dama dama)
during the early postcasting period. After the antlers are cast,
osteoclastic and osteoblastic activities lead to a smoothing of the
pedicle's separation surface, a strengthening of the pedicle bone, and a
partial restoration of the distal pedicle portion that was lost along
with the cast antler. Initially, bone formation occurs by
intramembranous ossification, but early during the regeneration process
cartilage is formed at the tips of the cranial appendages, and is
subsequently replaced by bone in a process of endochodral ossification.
Shortly after the antlers are cast, the cambium layer of the periosteum
in the distal pedicle is markedly enlarged, which suggests that the
periosteum serves as a cell source for the bone‐forming tissue covering
the exposed pedicle bone. The histological findings of our study are
consistent with the view that the bony component of the regenerating
cranial appendages of deer is largely derived from the pedicle
periosteum. Based on findings in other bone systems, we speculate that
stem cells that can undergo both osteogenic and chondrogenic
differentiation are present in the pedicle periosteum. The early onset
of chondrogenesis in the regeneration process is regarded as an
adaptation to the necessity of producing a huge volume of bone within a
short period. This parallels the situation in other cases of
chondrogenesis in membrane bones.

Harvard Citation style: Kierdorf, U., Stoffels, E., Stoffels, D., Kierdorf, H., Szuwart, T. and Clemen, G. (2003) Histological studies of bone formation during pedicle restoration and early antler regeneration in roe deer and fallow deer, Anatomical Record, 273A(2), pp. 741-751. https://doi.org/10.1002/ar.a.10082

APA Citation style: Kierdorf, U., Stoffels, E., Stoffels, D., Kierdorf, H., Szuwart, T., & Clemen, G. (2003). Histological studies of bone formation during pedicle restoration and early antler regeneration in roe deer and fallow deer. Anatomical Record. 273A(2), 741-751. https://doi.org/10.1002/ar.a.10082