Sammelbandbeitrag

Erschienen in: Signal Transduction and Protein Phosphorylation

Herausgeberliste: Heilmeyer, LMG

Jahr der Veröffentlichung: 1987

Seiten: 357-361

ISBN: 978-1-4757-0168-5

eISBN: 978-1-4757-0166-1

DOI Link: https://doi.org/10.1007/978-1-4757-0166-1_46

Serientitel: NATO ASI Series - A

Serienzählung: 135

Abstract: 

Interleukin 1 (IL-1) is a protein produced mainly by activated mononuclear phagocytes which mediates the accessory cell requirement in the activation cascade of T-lymphocytes. The purification and molecular cloning of at least two different genes for IL-1 made larger amounts of the molecule available and thus it became apparent that the IL-1s have a multitude of functions besides the central role in the immune system, which can be summarized in their regulatory function in the inflammatory response (for a review see (1)). Despite this pivotal role of IL-1 in regulating the metabolism and controlling the growth of a variety of target cells, very few data are available concerning the ways of signal transduction involved.Interleukin 1 (IL-1) is a protein produced mainly by activated mononuclear phagocytes which mediates the accessory cell requirement in the activation cascade of T-lymphocytes. The purification and molecular cloning of at least two different genes for IL-1 made larger amounts of the molecule available and thus it became apparent that the IL-1s have a multitude of functions besides the central role in the immune system, which can be summarized in their regulatory function in the inflammatory response (for a review see (1)). Despite this pivotal role of IL-1 in regulating the metabolism and controlling the growth of a variety of target cells, very few data are available concerning the ways of signal transduction involved.

Harvard-Zitierstil: Martin, M., Kyas, U. and Resch, K. (1987) Interleukin 1 Induces Tyrosine Phosphorylation in Plasma Membranes of the Tumor Cell Lines K 562 and BW 5147, in Heilmeyer, L. (ed.) Signal Transduction and Protein Phosphorylation. Boston: Springer, pp. 357-361. https://doi.org/10.1007/978-1-4757-0166-1_46

APA-Zitierstil: Martin, M., Kyas, U., & Resch, K. (1987). Interleukin 1 Induces Tyrosine Phosphorylation in Plasma Membranes of the Tumor Cell Lines K 562 and BW 5147. In Heilmeyer, L. (Ed.), Signal Transduction and Protein Phosphorylation (pp. 357-361). Springer. https://doi.org/10.1007/978-1-4757-0166-1_46