Journal article

Cycloaromatization of 1,4-pentadiynes: A viable possibility?


Authors list: Kawatkar, SP; Schreiner, PR

Publication year: 2002

Pages: 3643-3646

Journal: Organic Letters

Volume number: 4

Issue number: 21

ISSN: 1523-7060

DOI Link: https://doi.org/10.1021/ol0266424

Publisher: American Chemical Society


Abstract: 
The effects of several mostly or-withdrawing, pi-donating substituents X on the hitherto unknown Bergman-like cyclizations of 3-substituted 1,4-pentadiynes were studied at the BLYP/6-311+G*//BLYP/6-31G* level of theory. As the cyclization with X = OH+ has the lowest barrier and is about thermoneutral, we predict that the title reaction is viable, for instance, through activation of derivatives with X = 0 with Lewis acids.



Citation Styles

Harvard Citation style: Kawatkar, S. and Schreiner, P. (2002) Cycloaromatization of 1,4-pentadiynes: A viable possibility?, Organic Letters, 4(21), pp. 3643-3646. https://doi.org/10.1021/ol0266424

APA Citation style: Kawatkar, S., & Schreiner, P. (2002). Cycloaromatization of 1,4-pentadiynes: A viable possibility?. Organic Letters. 4(21), 3643-3646. https://doi.org/10.1021/ol0266424


Last updated on 2025-21-05 at 15:22