Journal article

Publication year: 2011

Pages: 10987-10989

Journal: Biochemistry

Volume number: 50

Issue number: 51

ISSN: 0006-2960

DOI Link: https://doi.org/10.1021/bi201504a

Publisher: American Chemical Society

Abstract: 
The red/far-red-sensing biological photoreceptor phytochrome is a paradigmatic two-state signaling system. The two thermally stable states are interconverted via a photoreaction of the covalently bound tetrapyrrole chromophore. Applying recently developed solid-state nuclear magnetic resonance, we study both the chromophore and its protein pocket in the Pr (red-absorbing) and Pfr (far-red-absorbing) states. The observations show that the phototransformation combines local chemical reactions with a mesoscopic transition of order. Both the chromophore and its binding pocket are quasi-liquid and disordered in Pr, yet quasi-solid and ordered in Pfr. Possible biochemical implications are discussed.

Harvard Citation style: Song, C., Psakis, G., Lang, C., Mailliet, J., Zaanen, J., Gartner, W., et al. (2011) On the Collective Nature of Phytochrome Photoactivation, Biochemistry, 50(51), pp. 10987-10989. https://doi.org/10.1021/bi201504a

APA Citation style: Song, C., Psakis, G., Lang, C., Mailliet, J., Zaanen, J., Gartner, W., Hughes, J., & Matysik, J. (2011). On the Collective Nature of Phytochrome Photoactivation. Biochemistry. 50(51), 10987-10989. https://doi.org/10.1021/bi201504a