Journalartikel

Jahr der Veröffentlichung: 2004

Seiten: 761-769

Zeitschrift: British Journal of Cancer

Bandnummer: 90

Heftnummer: 4

ISSN: 0007-0920

DOI Link: https://doi.org/10.1038/sj.bjc.6601575

Verlag: Springer Nature [academic journals on nature.com]

Abstract: 
Covalent modifications of histories, such as acetylation, methylation, and phosphorylation, and other epigenetic modulations of the chromatin, such as methylation of DNA and ATP-dependent chromatin reorganisation, can play a major part in the multistep process of carcinogenesis, with far-reaching implications for human biology and human health. This review focuses on how aberrant covalent histone modifications may contribute to the development of a variety of human cancers, and discusses the recent findings with regard to potential therapies.

Harvard-Zitierstil: Hake, S., Xiao, A. and Allis, C. (2004) Linking the epigenetic 'language' of covalent histone modifications to cancer, British Journal of Cancer, 90(4), pp. 761-769. https://doi.org/10.1038/sj.bjc.6601575

APA-Zitierstil: Hake, S., Xiao, A., & Allis, C. (2004). Linking the epigenetic 'language' of covalent histone modifications to cancer. British Journal of Cancer. 90(4), 761-769. https://doi.org/10.1038/sj.bjc.6601575