Journalartikel

Association of hydroxamate siderophore (aerobactin) with Escherichia coli isolated from patients with bacteremia.


AutorenlisteMontgomerie, JZ; Bindereif, A; Neilands, JB; Kalmanson, GM; Guze, LB

Jahr der Veröffentlichung1984

Seiten835-838

ZeitschriftInfection and Immunity

Bandnummer46

Heftnummer3

ISSN0019-9567

eISSN1098-5522

URLhttps://www.ncbi.nlm.nih.gov/pubmed/6389366

VerlagAmerican Society for Microbiology


Abstract
Clinical isolates of Escherichia coli were examined for the presence of hydroxamate siderophore (aerobactin). The incidence of aerobactin-positive strains of E. coli from the blood was greater than the incidence of these strains isolated from other sites. The presence of aerobactin and the virulence of strains of E. coli in urinary tract infection were also examined in mice. The presence of aerobactin in the strains of E. coli correlated with virulence as measured by proportion of deaths but not with renal infection. These results suggest that the presence of aerobactin may be a significant factor in the invasion of the blood stream.



Zitierstile

Harvard-ZitierstilMontgomerie, J., Bindereif, A., Neilands, J., Kalmanson, G. and Guze, L. (1984) Association of hydroxamate siderophore (aerobactin) with Escherichia coli isolated from patients with bacteremia., Infection and Immunity, 46(3), pp. 835-838. https://www.ncbi.nlm.nih.gov/pubmed/6389366

APA-ZitierstilMontgomerie, J., Bindereif, A., Neilands, J., Kalmanson, G., & Guze, L. (1984). Association of hydroxamate siderophore (aerobactin) with Escherichia coli isolated from patients with bacteremia.. Infection and Immunity. 46(3), 835-838. https://www.ncbi.nlm.nih.gov/pubmed/6389366


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