Journal article

Comparative Pathway Analyzer - a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organisms


Authors listOehm, S; Gilbert, D; Tauch, A; Stoye, J; Goesmann, A

Publication year2008

PagesW433-W437

JournalNucleic Acids Research

Volume number36

Issue numberSupplement 2

ISSN0305-1048

eISSN1362-4962

DOI Linkhttps://doi.org/10.1093/nar/gkn284

PublisherOxford University Press


Abstract
In order to understand the phenotype of any living system, it is essential to not only investigate its genes, but also the specific metabolic pathway variant of the organism of interest, ideally in comparison with other organisms. The Comparative Pathway Analyzer, CPA, calculates and displays the differences in metabolic reaction content between two sets of organisms. Because results are highly dependent on the distribution of organisms into these two sets and the appropriate definition of these sets often is not easy, we provide hierarchical clustering methods for the identification of significant groupings. CPA also visualizes the reaction content of several organisms simultaneously allowing easy comparison. Reaction annotation data and maps for visualizing the results are taken from the KEGG database. Additionally, users can upload their own annotation data. This website is free and open to all users and there is no login requirement.



Citation Styles

Harvard Citation styleOehm, S., Gilbert, D., Tauch, A., Stoye, J. and Goesmann, A. (2008) Comparative Pathway Analyzer - a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organisms, Nucleic Acids Research, 36(Supplement 2), pp. W433-W437. https://doi.org/10.1093/nar/gkn284

APA Citation styleOehm, S., Gilbert, D., Tauch, A., Stoye, J., & Goesmann, A. (2008). Comparative Pathway Analyzer - a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organisms. Nucleic Acids Research. 36(Supplement 2), W433-W437. https://doi.org/10.1093/nar/gkn284


Last updated on 2025-21-05 at 15:40