Journalartikel

Jahr der Veröffentlichung: 2018

Seiten: 10070-10079

Zeitschrift: The Journal of Organic Chemistry

Bandnummer: 83

Heftnummer: 17

ISSN: 0022-3263

DOI Link: https://doi.org/10.1021/acs.joc.8b01392

Verlag: American Chemical Society

Abstract: 
Phenol moieties are key structural motifs in many areas of chemical research from polymers to pharmaceuticals. Herein, we report on the design and use of a structurally demanding cyclic peroxide (spiro [bicyclo [2.2.1 ]heptane-2,4'- [1,2] dioxolane] -3 ',5'-dione, P4) for the direct hydroxylation of aromatic substrates. The new peroxide benefits from high thermal stability and can be synthesized from readily available starting materials. The aromatic C-H oxidation using P4 exhibits generally good yields (up to 96%) and appreciable regioselectivities.

Harvard-Zitierstil: Pilevar, A., Hosseini, A., Sekutor, M., Hausmann, H., Becker, J., Turke, K., et al. (2018) Tuning the Reactivity of Peroxo Anhydrides for Aromatic C-H Bond Oxidation, The Journal of Organic Chemistry, 83(17), pp. 10070-10079. https://doi.org/10.1021/acs.joc.8b01392

APA-Zitierstil: Pilevar, A., Hosseini, A., Sekutor, M., Hausmann, H., Becker, J., Turke, K., & Schreiner, P. (2018). Tuning the Reactivity of Peroxo Anhydrides for Aromatic C-H Bond Oxidation. The Journal of Organic Chemistry. 83(17), 10070-10079. https://doi.org/10.1021/acs.joc.8b01392