Journal article
Authors list: Heinrich, Andre Patrick; Pooda, Sié Hermann; Porciani, Angélique; Zéla, Lamidi; Schinzel, Alexandra; Moiroux, Nicolas; Roberge, Christophe; Martina, Marie-Sophie; Courjaud, Anne-Laure; Dabiré, Roch K; Römbke, Jörg; Düring, Rolf-Alexander; Mouline, Karine
Publication year: 2024
Pages: 724-736
Journal: Nature Sustainability
Volume number: 7
Issue number: 6
ISSN: 2398-9629
Open access status: Hybrid
DOI Link: https://doi.org/10.1038/s41893-024-01332-8
Publisher: Nature Research
Malaria remains an enduring challenge in sub-Saharan Africa, affecting public health and development. Control measures can include the use of insecticides that target adult Anopheles mosquitoes transmitting the malaria-causing Plasmodium parasite. Such mosquitoes can also bite livestock, allowing vector populations to be maintained at levels that enable parasite transmission. Thus, one way to control the spread of malaria includes the use of endectocide-treated livestock which renders the blood of cattle toxic to such mosquito populations. Here we present an ecotoxicological perspective on malaria vector control, using cattle treated with the endectocide ivermectin to target zoophagic and opportunistic Anopheles coluzzii mosquitoes. Our study employs an innovative, long-acting injectable ivermectin formulation with over 6 months of sustained mosquitocidal activity. Robust vector population modelling underscores its promising field effectiveness. Environmental implications (soil sorption and dissipation) of excreted ivermectin and potential ecotoxicological risks to non-target dung organisms in West Africa are discussed, in addition to actionable, locally inspired risk mitigation measures to protect sub-Saharan soils and agroecosystems from chemical pollution. We highlight how ecotoxicology and environmental chemistry improve livestock-based vector control with ivermectin for effective and more sustainable malaria management.
Abstract:
Citation Styles
Harvard Citation style: Heinrich, A., Pooda, S., Porciani, A., Zéla, L., Schinzel, A., Moiroux, N., et al. (2024) An ecotoxicological view on malaria vector control with ivermectin-treated cattle, Nature Sustainability, 7(6), pp. 724-736. https://doi.org/10.1038/s41893-024-01332-8
APA Citation style: Heinrich, A., Pooda, S., Porciani, A., Zéla, L., Schinzel, A., Moiroux, N., Roberge, C., Martina, M., Courjaud, A., Dabiré, R., Römbke, J., Düring, R., & Mouline, K. (2024). An ecotoxicological view on malaria vector control with ivermectin-treated cattle. Nature Sustainability. 7(6), 724-736. https://doi.org/10.1038/s41893-024-01332-8
