Journal article
Authors list: Sorensen, Mette; Pershagen, Goran; Thacher, Jesse Daniel; Lanki, Timo; Wicki, Benedikt; Roosli, Martin; Vienneau, Danielle; Cantuaria, Manuella Lech; Schmidt, Jesper Hvass; Aasvang, Gunn Marit; Al-Kindi, Sadeer; Osborne, Michael T.; Wenzel, Philip; Sastre, Juan; Fleming, Ingrid; Schulz, Rainer; Hahad, Omar; Kuntic, Marin; Zielonka, Jacek; Sies, Helmut; Grune, Tilman; Frenis, Katie; Munzel, Thomas; Daiber, Andreas
Publication year: 2024
Journal: Redox Biology
Volume number: 69
ISSN: 2213-2317
Open access status: Gold
DOI Link: https://doi.org/10.1016/j.redox.2023.102995
Publisher: Elsevier
Abstract:
Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart disease. In contrast, they concluded that the quality of evidence for a link to other diseases was very low to moderate. Since then, several studies on the impact of noise on various diseases have been published. Also, studies investigating the mechanistic pathways underlying noise-induced health effects are emerging. We review the current evidence regarding effects of noise on health and the related disease-mechanisms. Several high-quality cohort studies consistently found road traffic noise to be associated with a higher risk of ischemic heart disease, heart failure, diabetes, and all-cause mortality. Furthermore, recent studies have indicated that road traffic and railway noise may increase the risk of diseases not commonly investigated in an environmental noise context, including breast cancer, dementia, and tinnitus. The harmful effects of noise are related to activation of a physiological stress response and nighttime sleep disturbance. Oxidative stress and inflammation downstream of stress hormone signaling and dysregulated circadian rhythms are identified as major disease-relevant pathomechanistic drivers. We discuss the role of reactive oxygen species and present results from antioxidant interventions. Lastly, we provide an overview of oxidative stress markers and adverse redox processes reported for noise-exposed animals and humans. This position paper summarizes all available epidemiological, clinical, and preclinical evidence of transportation noise as an important environmental risk factor for public health and discusses its implications on the population level.
Citation Styles
Harvard Citation style: Sorensen, M., Pershagen, G., Thacher, J., Lanki, T., Wicki, B., Roosli, M., et al. (2024) Health position paper and redox perspectives - Disease burden by transportation noise, Redox Biology, 69, Article 102995. https://doi.org/10.1016/j.redox.2023.102995
APA Citation style: Sorensen, M., Pershagen, G., Thacher, J., Lanki, T., Wicki, B., Roosli, M., Vienneau, D., Cantuaria, M., Schmidt, J., Aasvang, G., Al-Kindi, S., Osborne, M., Wenzel, P., Sastre, J., Fleming, I., Schulz, R., Hahad, O., Kuntic, M., Zielonka, J., ...Daiber, A. (2024). Health position paper and redox perspectives - Disease burden by transportation noise. Redox Biology. 69, Article 102995. https://doi.org/10.1016/j.redox.2023.102995
Keywords
Adverse redox signaling; AMBIENT AIR-POLLUTION; EFFORT-REWARD IMBALANCE; Environmental risk factors; INDUCED OXIDATIVE STRESS; LOW-FREQUENCY NOISE; NITRIC-OXIDE SYNTHASE; Non-communicable diseases; Oxidative stress and inflammation; RENIN-ANGIOTENSIN SYSTEM; ROAD TRAFFIC NOISE; Stress hormones; TEMPORARY THRESHOLD SHIFT; Transportation noise; VASCULAR SUPEROXIDE-PRODUCTION
