Journal article
Authors list: Mueller, Jana; Erokhina, Anna; Gletscher, Isabell; Mittenzwei, Frank; Mueller, Janina; Schikowski, Lisa; Cigler, Pia; Henrich, Manfred
Publication year: 2023
Pages: 368-374
Journal: Tierärztliche Praxis, Ausgabe K: Kleintiere, Heimtiere
Volume number: 51
Issue number: 05
ISSN: 1434-1239
eISSN: 2567-5842
DOI Link: https://doi.org/10.1055/a-2180-5893
Publisher: Thieme Publishing
Abstract:
A 50-year-old female Hermann's tortoise ( Testudo hermannii boettgeri ) was presented with anorexia and lethargy. Clinical examination revealed multiple, visually inconspicuous but indentable areas in the shell corresponding to osteolysis radiographically. Soft tissue nodules and osteolytic lesions were also noted in the limbs. Laboratory results revealed elevated aspartate aminotransferase activity and uric acid concentrations, hypoglycemia, and hyperphosphatemia. Klebsiella oxytoca was isolated from a biopsied scutal area, and the biopsy suggested neoplasia. After a short period of clinical improvement, the animal's condition deteriorated, and it died. Post mortem computed tomography revealed polyostotic lytic lesions of multiple bones and the shell with associated soft tissue nodules protruding into the coelom, and nodular lung lesions. Necropsy, histopathology, and immunohistochemistry secured a diagnosis of a poorly differentiated, pan-cytokeratin-positive squamous cell carcinoma with widespread soft tissue and bone metastases, osteolysis and desmoplasia.
Citation Styles
Harvard Citation style: Mueller, J., Erokhina, A., Gletscher, I., Mittenzwei, F., Mueller, J., Schikowski, L., et al. (2023) Metastasizing squamous cell carcinoma in a 50-year-old Eastern Hermann's tortoise ( Testudo hermannii boettgeri ), Tierärztliche Praxis, Ausgabe K: Kleintiere, Heimtiere, 51(05), pp. 368-374. https://doi.org/10.1055/a-2180-5893
APA Citation style: Mueller, J., Erokhina, A., Gletscher, I., Mittenzwei, F., Mueller, J., Schikowski, L., Cigler, P., & Henrich, M. (2023). Metastasizing squamous cell carcinoma in a 50-year-old Eastern Hermann's tortoise ( Testudo hermannii boettgeri ). Tierärztliche Praxis, Ausgabe K: Kleintiere, Heimtiere. 51(05), 368-374. https://doi.org/10.1055/a-2180-5893
Keywords
BEARDED DRAGONS; chelonian; REPTILES; Testudinidae
