Journalartikel

Jahr der Veröffentlichung: 2023

Zeitschrift: Molecular Catalysis

Bandnummer: 549

ISSN: 2468-8231

DOI Link: https://doi.org/10.1016/j.mcat.2023.113451

Verlag: Elsevier

Abstract: 
A clean and selective "on-water-on-air" oxidation of primary alcohols to the corresponding aldehydes with mycelium lyophilisates of the non-toxic white-rot fungus Bjerkandera adusta was developed. The biocatalytic protocol is simple and the catalyst is readily accessible as a powder, which could be stored at least for 7 months without changes of activity. The catalytic activity of the fungus is associated with the presence of aryl-alcohol oxidase, that was isolated from the lyophilisate and characterised. Remarkably, a dichotomy in the fungal reactivity was observed, as the corresponding growing cultures catalyse the reverse process, selectively reducing aldehydes to the corresponding alcohols. Enzymatic oxidations by B. adusta are an excellent non-toxic alternative to metal-mediated oxidations in the lab with potential in food, beverage, cosmetic, and pharmaceutical industries, as it tolerates many functional groups.

Harvard-Zitierstil: V. Babkina, V., Albuquerque, W., Haiduk, Y., Michalak, W., Ghezellou, P., Zorn, H., et al. (2023) Fungal lyophilisates as catalysts for organic synthesis: Preparative oxidations with the white-rot fungus Bjerkandera adusta, MOLECULAR CATALYSIS, 549, Article 113451. https://doi.org/10.1016/j.mcat.2023.113451

APA-Zitierstil: V. Babkina, V., Albuquerque, W., Haiduk, Y., Michalak, W., Ghezellou, P., Zorn, H., & Zhuk, T. (2023). Fungal lyophilisates as catalysts for organic synthesis: Preparative oxidations with the white-rot fungus Bjerkandera adusta. MOLECULAR CATALYSIS. 549, Article 113451. https://doi.org/10.1016/j.mcat.2023.113451