Journalartikel
Autorenliste: Dramburg, Stephanie; Hilger, Christiane; Santos, Alexandra F.; de las Vecillas, Leticia; Aalberse, Rob C.; Acevedo, Nathalie; Aglas, Lorenz; Altmann, Friedrich; Arruda, Karla L.; Asero, Riccardo; Ballmer-Weber, Barbara; Barber, Domingo; Beyer, Kirsten; Biedermann, Tilo; Bilo, Maria Beatrice; Blank, Simon; Bosshard, Philipp P.; Breiteneder, Heimo; Brough, Helen A.; Bublin, Merima; Campbell, Dianne; Caraballo, Luis; Caubet, Jean Christoph; Celi, Giorgio; Chapman, Martin D.; Chruszcz, Maksymilian; Custovic, Adnan; Czolk, Rebecca; Davies, Janet; Douladiris, Nikolaos; Eberlein, Bernadette; Ebisawa, Motohiro; Ehlers, Anna; Eigenmann, Philippe; Gadermaier, Gabriele; Giovannini, Mattia; Gomez, Francisca; Grohman, Rebecca; Guillet, Carole; Hafner, Christine; Hamilton, Robert G.; Hauser, Michael; Hawranek, Thomas; Hoffmann, Hans Juergen; Holzhauser, Thomas; Iizuka, Tomona; Jacquet, Alain; Jakob, Thilo; Janssen-Weets, Bente; Jappe, Uta; Jutel, Marek; Kalic, Tanja; Kamath, Sandip; Kespohl, Sabine; Kleine-Tebbe, Joerg; Knol, Edward; Knulst, Andre; Konradsen, Jon R.; Korosec, Peter; Kuehn, Annette; Lack, Gideon; Le, Thuy-My; Lopata, Andreas; Luengo, Olga; Maekelae, Mika; Marra, Alessandro Maria; Mills, Clare; Morisset, Martine; Muraro, Antonella; Nowak-Wegrzyn, Anna; Nugraha, Roni; Ollert, Markus; Palosuo, Kati; Pastorello, Elide Anna; Patil, Sarita Ulhas; Platts-Mills, Thomas; Pomes, Anna; Poncet, Pascal; Potapova, Ekaterina; Poulsen, Lars K.; Radauer, Christian; Radulovic, Suzana; Raulf, Monika; Rouge, Pierre; Sastre, Joaquin; Sato, Sakura; Scala, Enrico; Schmid, Johannes M.; Schmid-Grendelmeier, Peter; Schrama, Denise; Senechal, Helene; Traidl-Hoffmann, Claudia; Valverde-Monge, Marcela; van Hage, Marianne; van Ree, Ronald; Verhoeckx, Kitty; Vieths, Stefan; Wickman, Magnus; Zakzuk, Josefina; Matricardi, Paolo M.; Hoffmann-Sommergruber, Karin
Jahr der Veröffentlichung: 2023
Zeitschrift: Pediatric Allergy and Immunology
Bandnummer: 34
ISSN: 0905-6157
eISSN: 1399-3038
DOI Link: https://doi.org/10.1111/pai.13854
Verlag: Wiley
Abstract:
Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967, our knowledge about the immunological mechanisms of IgE-mediated allergies has remarkably increased. In addition to understanding the immune response and clinical symptoms, allergy diagnosis and management depend strongly on the precise identification of the elicitors of the IgE-mediated allergic reaction. In the past four decades, innovations in bioscience and technology have facilitated the identification and production of well-defined, highly pure molecules for component-resolved diagnosis (CRD), allowing a personalized diagnosis and management of the allergic disease for individual patients. The first edition of the "EAACI Molecular Allergology User's Guide" (MAUG) in 2016 rapidly became a key reference for clinicians, scientists, and interested readers with a background in allergology, immunology, biology, and medicine. Nevertheless, the field of molecular allergology is moving fast, and after 6 years, a new EAACI Taskforce was established to provide an updated document. The Molecular Allergology User's Guide 2.0 summarizes state-of-the-art information on allergen molecules, their clinical relevance, and their application in diagnostic algorithms for clinical practice. It is designed for both, clinicians and scientists, guiding health care professionals through the overwhelming list of different allergen molecules available for testing. Further, it provides diagnostic algorithms on the clinical relevance of allergenic molecules and gives an overview of their biology, the basic mechanisms of test formats, and the application of tests to measure allergen exposure.
Zitierstile
Harvard-Zitierstil: Dramburg, S., Hilger, C., Santos, A., de las Vecillas, L., Aalberse, R., Acevedo, N., et al. (2023) EAACI Molecular Allergology User's Guide 2.0, Pediatric Allergy and Immunology, 34, Article e13854. https://doi.org/10.1111/pai.13854
APA-Zitierstil: Dramburg, S., Hilger, C., Santos, A., de las Vecillas, L., Aalberse, R., Acevedo, N., Aglas, L., Altmann, F., Arruda, K., Asero, R., Ballmer-Weber, B., Barber, D., Beyer, K., Biedermann, T., Bilo, M., Blank, S., Bosshard, P., Breiteneder, H., Brough, H., ...Hoffmann-Sommergruber, K. (2023). EAACI Molecular Allergology User's Guide 2.0. Pediatric Allergy and Immunology. 34, Article e13854. https://doi.org/10.1111/pai.13854
Schlagwörter
allergy diagnosis; anaphylaxis; Atopic dermatitis; BASOPHIL ACTIVATION TEST; BET V 1; BIRCH POLLEN ALLERGEN; COMPONENT-RESOLVED DIAGNOSIS; COWS MILK ALLERGY; cross-reactive carbohydrates; diagnostic algorithms; gibberellin-regulated proteins; HOUSE-DUST MITE; IGE; IgE cross-reactivity; LIPID TRANSFER PROTEIN; lipocalins; molecular allergology; non-specific lipid transfer proteins; oleosins; pan-allergens; parvalbumins; pathogenesis-related protein family 10; polcalcins; pollen allergy; Precision medicine; profilins; REACTIVE CARBOHYDRATE DETERMINANTS; RED MEAT ALLERGY; seed storage proteins; serum albumins; tropomyosins
