Journal article

Prostate biopsy-infection prophylaxis and patient preparation


Authors listPilatz, A.; Alidjanov, J.; Bonkat, G.; Wagenlehner, F.

Publication year2023

Pages459-463

JournalDie Urologie

Volume number62

Issue number5

ISSN2731-7064

eISSN2731-7072

DOI Linkhttps://doi.org/10.1007/s00120-023-02065-w

PublisherSpringer


Abstract
Prostate biopsy has been at the center of controversy in recent years due to high infection complications associated with the transrectal route and the withdrawal of authorization for fluoroquinolones and fosfomycin trometemol as prophylaxis. The Urological Infections Guideline Group of the European Association of Urology (EAU) recently published a meta-analysis in two parts based on randomized controlled trials (RCTs) and annually updates the data for the EAU guidelines. The meta-analyses show that transperineal prostate biopsy is associated with significantly fewer infectious complications than transrectal biopsy and should therefore be preferred. If transrectal biopsy is still used, then intrarectal cleansing with povidone-iodine and antibiotic prophylaxis should be used. Antibiotic prophylaxis strategies include targeted prophylaxis after sensitivity testing of the rectal flora, augmented prophylaxis with several antibiotics and empirical monoprophylaxis. Data from RCTs are available for aminoglycosides and third-generation cephalosporins.



Citation Styles

Harvard Citation stylePilatz, A., Alidjanov, J., Bonkat, G. and Wagenlehner, F. (2023) Prostate biopsy-infection prophylaxis and patient preparation, Die Urologie, 62(5), pp. 459-463. https://doi.org/10.1007/s00120-023-02065-w

APA Citation stylePilatz, A., Alidjanov, J., Bonkat, G., & Wagenlehner, F. (2023). Prostate biopsy-infection prophylaxis and patient preparation. Die Urologie. 62(5), 459-463. https://doi.org/10.1007/s00120-023-02065-w



Keywords


Antibiotic prophylaxisfosfomycinInfectious complicationsIntrarektale DesinfektionMagnetic Resonance ImagingPAPERProstate-specific antigen

Last updated on 2025-21-05 at 18:14