Journal article

Fetal Brain Tumors, a Challenge in Prenatal Diagnosis, Counselling, and Therapy


Authors listBedei, Ivonne Alexandra; Huisman, Thierry A. G. M.; Whitehead, William; Axt-Fliedner, Roland; Belfort, Michael; Sanz Cortes, Magdalena

Publication year2023

JournalJournal of Clinical Medicine

Volume number12

Issue number1

eISSN2077-0383

Open access statusGold

DOI Linkhttps://doi.org/10.3390/jcm12010058

PublisherMDPI


Abstract
Fetal brain tumors are a rare entity with an overall guarded prognosis. About 10% of congenital brain tumors are diagnosed during fetal life. They differ from the postnatally encountered pediatric brain tumors with respect to location and tumor type. Fetal brain tumors can be benign or malignant and infiltrate or displace adjacent brain structures. Due to their high mitotic rate, they can show rapid growth. Outcome depends on age of diagnosis, size, and histological tumor type. Findings like polyhydramnios and macrocephaly encountered on routine ultrasound are frequently associated. Detailed prenatal anomaly scan and subsequent fetal magnetic resonance imaging (MRI) may identify the brain tumor and its severity. Both maternal and fetal prognosis should be included in prenatal counselling and decision making.



Citation Styles

Harvard Citation styleBedei, I., Huisman, T., Whitehead, W., Axt-Fliedner, R., Belfort, M. and Sanz Cortes, M. (2023) Fetal Brain Tumors, a Challenge in Prenatal Diagnosis, Counselling, and Therapy, Journal of Clinical Medicine, 12(1), Article 58. https://doi.org/10.3390/jcm12010058

APA Citation styleBedei, I., Huisman, T., Whitehead, W., Axt-Fliedner, R., Belfort, M., & Sanz Cortes, M. (2023). Fetal Brain Tumors, a Challenge in Prenatal Diagnosis, Counselling, and Therapy. Journal of Clinical Medicine. 12(1), Article 58. https://doi.org/10.3390/jcm12010058



Keywords


fetal brain tumorhydrocephalusmacrocephalyprenatal imagingTeratoma

Last updated on 2025-10-06 at 11:48