Journalartikel

Jahr der Veröffentlichung: 2023

Seiten: 1362-1371

Zeitschrift: Clinical Research in Cardiology

Bandnummer: 112

Heftnummer: 10

ISSN: 1861-0684

eISSN: 1861-0692

Open Access Status: Hybrid

DOI Link: https://doi.org/10.1007/s00392-022-02099-8

Verlag: Springer

Abstract: 
Background Reference values for right ventricular function and pulmonary circulation coupling were recently established for the general population. However, normative values for elite athletes are missing, even though exercise-related right ventricular enlargement is frequent in competitive athletes. Methods We examined 497 healthy male elite athletes (age 26.1 +/- 5.2 years) of mixed sports with a standardized transthoracic echocardiographic examination. Tricuspid annular plane excursion (TAPSE) and systolic pulmonary artery pressure (SPAP) were measured. Pulmonary circulation coupling was calculated as TAPSE/SPAP ratio. Two age groups were defined (18-29 years and 30-39 years) and associations of clinical parameters with the TAPSE/SPAP ratio were determined and compared for each group. Results Athletes aged 18-29 (n = 349, 23.8 +/- 3.5 years) displayed a significantly lower TAPSE/SPAP ratio (1.23 +/- 0.3 vs. 1.31 +/- 0.33 mm/mmHg, p = 0.039), TAPSE/SPAP to body surface area (BSA) ratio (0.56 +/- 0.14 vs. 0.6 +/- 0.16 mm*m(2)/mmHg, p = 0.017), diastolic blood pressure (75.6 +/- 7.9 vs. 78.8 +/- 10.7 mmHg, p < 0.001), septal wall thickness (10.2 +/- 1.1 vs. 10.7 +/- 1.1 mm, p = 0.013) and left atrial volume index (27.5 +/- 4.5 vs. 30.8 +/- 4.1 ml/m(2), p < 0.001), but a higher SPAP (24.2 +/- 4.5 vs. 23.2 +/- 4.4 mmHg, p = 0.035) compared to athletes aged 30-39 (n = 148, 33.1 +/- 3.4 years). TAPSE was not different between the age groups. The TAPSE/SPAP ratio was positively correlated with left ventricular stroke volume (r = 0.133, p = 0.018) and training amount per week (r = 0.154, p = 0.001) and negatively correlated with E/E ' lat. (r = -0.152, p = 0.005). Conclusion The reference values for pulmonary circulation coupling determined in this study could be used to interpret and distinguish physiological from pathological cardiac remodeling in male elite athletes.

Harvard-Zitierstil: Bauer, P., Tello, K., Kraushaar, L., Doerr, O., Keranov, S., Husain-Syed, F., et al. (2023) Normative values of non-invasively assessed RV function and pulmonary circulation coupling for pre-participation screening derived from 497 male elite athletes, Clinical Research in Cardiology, 112(10), pp. 1362-1371. https://doi.org/10.1007/s00392-022-02099-8

APA-Zitierstil: Bauer, P., Tello, K., Kraushaar, L., Doerr, O., Keranov, S., Husain-Syed, F., Nef, H., Hamm, C., & Most, A. (2023). Normative values of non-invasively assessed RV function and pulmonary circulation coupling for pre-participation screening derived from 497 male elite athletes. Clinical Research in Cardiology. 112(10), 1362-1371. https://doi.org/10.1007/s00392-022-02099-8