Journalartikel

Complications of balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: Impact on the outcome


AutorenlisteWiedenroth, Christoph B.; Deissner, Henrike; Adameit, Miriam S. D.; Kriechbaum, Steffen D.; Ghofrani, H. -Ardeschir; Breithecker, Andreas; Haas, Moritz; Roller, Fritz; Rolf, Andreas; Hamm, Christian W.; Mayer, Eckhard; Guth, Stefan; Liebetrau, Christoph

Jahr der Veröffentlichung2022

Seiten1086-1094

ZeitschriftThe Journal of Heart and Lung Transplantation

Bandnummer41

Heftnummer8

ISSN1053-2498

eISSN1557-3117

DOI Linkhttps://doi.org/10.1016/j.healun.2022.05.002

VerlagElsevier


Abstract
BACKGROUND: Balloon pulmonary angioplasty (BPA) is an emerging interventional treatment for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) that targets subsegmental branches of the pulmonary artery. As the reported complication rates are high, the aim of the present study was to evaluate the effects of certain complications on the outcome after treatment. METHODS: From March 2014 to December 2019, a total of 235 patients with inoperable CTEPH under-went BPA. Of these patients, 140 were included who completed a follow-up examination 6 months after the last intervention; another 2 patients deceased due to complications of BPA. RESULTS: A high baseline pulmonary vascular resistance (PVR) > 6.6 WU correlated with a higher rate of complications (mostly pulmonary artery perforations). Wire perforation during BPA did not correlate with worse outcome in terms of PVR reduction. The complication rate per intervention decreased from 21% to 14% during the 5 year period of the study. CONCLUSIONS: Complications are frequently observed in BPA, but the mortality rate is very low in expert centers. Importantly, the occurrence of complications does not portend a worse outcome. (C) 2022 International Society for Heart and Lung Transplantation. All rights reserved.



Zitierstile

Harvard-ZitierstilWiedenroth, C., Deissner, H., Adameit, M., Kriechbaum, S., Ghofrani, H., Breithecker, A., et al. (2022) Complications of balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: Impact on the outcome, The Journal of Heart and Lung Transplantation, 41(8), pp. 1086-1094. https://doi.org/10.1016/j.healun.2022.05.002

APA-ZitierstilWiedenroth, C., Deissner, H., Adameit, M., Kriechbaum, S., Ghofrani, H., Breithecker, A., Haas, M., Roller, F., Rolf, A., Hamm, C., Mayer, E., Guth, S., & Liebetrau, C. (2022). Complications of balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: Impact on the outcome. The Journal of Heart and Lung Transplantation. 41(8), 1086-1094. https://doi.org/10.1016/j.healun.2022.05.002



Schlagwörter


BALLOON PULMONARY ANGIOPLASTYChronic thromboembolic pulmonary hypertensionCOMPLICATIONShemodynamicsrisk factors, outcome


Nachhaltigkeitsbezüge


Zuletzt aktualisiert 2025-21-05 um 18:16