Journal article

Publication year: 2022

Pages: 596-601

Journal: Die Urologie

Volume number: 61

Issue number: 6

ISSN: 2731-7064

eISSN: 2731-7072

DOI Link: https://doi.org/10.1007/s00120-022-01832-5

Publisher: Springer

Abstract: 
Urinary tract infections (UTIs) are characterized by a broad clinical presentation ranging from uncomplicated cystitis to septic shock. 9-31% of all septicemias have a urogenital focus and are referred to as urosepsis. Urosepsis often occurs in the context of health system-associated infections. Obstructive uropathy (e.g., urolithiasis, tumors, strictures) is a major risk factor. The severity and course of urosepsis depend not only on the pathogenicity of the pathogen but also on the type and extent of the individual immune response. Therapy is divided into causal (antimicrobial therapy and focal sanitation), supportive (hemodynamic and pulmonal stabilization), and adjunctive (glucocorticoid and insulin therapy) therapy and should be initiated without delay. Due to demographic change, a further increase in urosepsis is expected in the future, so every urologist should be familiar with targeted diagnostics and effective therapy.

Harvard Citation style: Kranz, J., Stangl, F., Kuppe, C., Wagenlehner, F., Saar, M. and Schneidewind, L. (2022) Urosepsis-targeted diagnostics and effective therapy, Die Urologie, 61(6), pp. 596-601. https://doi.org/10.1007/s00120-022-01832-5

APA Citation style: Kranz, J., Stangl, F., Kuppe, C., Wagenlehner, F., Saar, M., & Schneidewind, L. (2022). Urosepsis-targeted diagnostics and effective therapy. Die Urologie. 61(6), 596-601. https://doi.org/10.1007/s00120-022-01832-5