Journal article

Publication year: 2022

Journal: Molecular and Cellular Pediatrics

Volume number: 9

Issue number: 1

eISSN: 2194-7791

Open access status: Gold

DOI Link: https://doi.org/10.1186/s40348-022-00139-x

Publisher: SpringerOpen

Abstract: 
BackgroundExclusive enteral nutrition (EEN) is the first-line therapy for pediatric-onset Crohn's disease (CD) patients. CEDATA-GPGE (R) is the largest patient registry for children and adolescents with inflammatory bowel disease (IBD) in Europe, collecting data from over 5000 patients since 2004 in Germany and Austria. Since the application of EEN over 8 weeks is difficult and a high dropout rate is often described, the mode of application including a supporting structure is crucial for success. The aim of this study was to ascertain the variation in the application of EEN across the participating centers and to associate these with the outcome.ResultsThirty-one centers responded to the survey (81.6%). 88.5% of CD patients were recommended EEN for induction therapy, 71.8% actually started with EEN, and 22.1% terminated the EEN prematurely. The duration of EEN typically lasted 6 to 8 weeks, and the polymeric formula was mainly used. 80.6% of the clinics added flavorings to the formulas. After EEN, the most preferred diet for maintenance therapy was a healthy, well-balanced diet considering individual intolerances.ConclusionsEEN is widely recommended as an induction therapy by the German and Austrian pediatric gastroenterologists for children and adolescents with CD. However, this questionnaire-based study has shown a wide variation in EEN protocols used by the different pediatric clinics of CEDATA-GPGE (R).

Harvard Citation style: Peters, S., Cantez, S. and De Laffolie, J. (2022) Implementation of exclusive enteral nutrition in pediatric patients with Crohn's disease-results of a survey of CEDATA-GPGE reporting centers, Molecular and Cellular Pediatrics, 9(1), Article 6. https://doi.org/10.1186/s40348-022-00139-x

APA Citation style: Peters, S., Cantez, S., & De Laffolie, J. (2022). Implementation of exclusive enteral nutrition in pediatric patients with Crohn's disease-results of a survey of CEDATA-GPGE reporting centers. Molecular and Cellular Pediatrics. 9(1), Article 6. https://doi.org/10.1186/s40348-022-00139-x