Journal article
Authors list: Wiedenroth, Christoph B.; Bandorski, Dirk; Ariobi, Kanischka; Ghofrani, H-Ardeschir; Lankeit, Mareike; Liebetrau, Christoph; Pruefer, Diethard; Mayer, Eckhard; Kriechbaum, Steffen D.; Guth, Stefan
Publication year: 2022
Pages: 663-670
Journal: The Thoracic and Cardiovascular Surgeon
Volume number: 70
Issue number: 08
ISSN: 0171-6425
eISSN: 1439-1902
DOI Link: https://doi.org/10.1055/s-0041-1740559
Publisher: Thieme Publishing / Georg Thieme Verlag
Abstract:
Background The gold standard treatment of patients with chronic thromboembolic pulmonary hypertension (CTEPH) is pulmonary endarterectomy (PEA). Little is known about the influence of advanced age on surgical outcome. Therefore, the aim of this study was to investigate the impact of patient's age on postoperative morbidity, mortality, and quality of life in a German referral center. Methods Prospectively collected data from 386 consecutive patients undergoing PEA between 01/2014 and 12/2016 were analyzed. Patients were divided into three groups according to their age: group 1: <= 50 years, group 2: > 50 <= 70 years, group 3: > 70 years. Results After PEA, distinct improvements in pulmonary hemodynamics, physical capacity (World Health Organization [WHO] functional class and 6-minute walking distance) and quality of life were found in all groups. There were more complications in elderly patients with longer time of invasive ventilation, intensive care, and in-hospital stay. However, the in-hospital mortality was comparable (0% in group 1, 2.6% in group 2, and 2.1% in group 3 [ p = 0.326]). Furthermore, the all-cause mortality at 1 year was 1.1% in group 1, 3.2% in group 2, and 6.3% in group 3 ( p = 0.122). Conclusions PEA is an effective treatment for CTEPH patients of all ages accompanied by low perioperative and 1-year mortality. CTEPH patients in advanced age carefully selected by thorough preoperative evaluation should be offered PEA in expert centers to improve quality of life, symptoms, and pulmonary hemodynamics.
Citation Styles
Harvard Citation style: Wiedenroth, C., Bandorski, D., Ariobi, K., Ghofrani, H., Lankeit, M., Liebetrau, C., et al. (2022) Does Age Matter? Pulmonary Endarterectomy in the Elderly Patient with CTEPH, The Thoracic and Cardiovascular Surgeon, 70(08), pp. 663-670. https://doi.org/10.1055/s-0041-1740559
APA Citation style: Wiedenroth, C., Bandorski, D., Ariobi, K., Ghofrani, H., Lankeit, M., Liebetrau, C., Pruefer, D., Mayer, E., Kriechbaum, S., & Guth, S. (2022). Does Age Matter? Pulmonary Endarterectomy in the Elderly Patient with CTEPH. The Thoracic and Cardiovascular Surgeon. 70(08), 663-670. https://doi.org/10.1055/s-0041-1740559
Keywords
ANGIOPLASTY; COMPLICATIONS; outcomes (includes mortality morbidity); Pulmonary embolism; Pulmonary vascular resistance
