Journal article

NITROFURANTOIN-INDUCED LUNG DISEASE WITH FATAL OUTCOME: A CASE REPORT


Authors listRolfes, Caroline; Dettmeyer, Reinhard; Hochscheid, Christopher

Publication year2021

Pages336-338

JournalRomanian Journal of Legal Medicine

Volume number29

Issue number3

ISSN1221-8618

DOI Linkhttps://doi.org/10.4323/rjlm.2021.336

PublisherROMANIAN LEGAL MED SOC


Abstract
An 81 year old patient was referred to our ECMO-center (extracorporeal membrane oxygenation) with acute respiratory distress syndrome after treatment with Nitrofurantoin for eight days. After ruling out other causes the diagnose "nitrofurantoin associated lung injury" was established and confirmed by CT-findings. Despite differentiated therapy and ECMO, clinically the patient passed away from finally occurred liver failure. Autopsy and histological examinations revealed extensive fibrosing and inflammatory processes in the lung tissue in the sense of drug-induced lung damage as well as signs of acute liver failure in the context of pre-final formation.



Citation Styles

Harvard Citation styleRolfes, C., Dettmeyer, R. and Hochscheid, C. (2021) NITROFURANTOIN-INDUCED LUNG DISEASE WITH FATAL OUTCOME: A CASE REPORT, Romanian Journal of Legal Medicine, 29(3), pp. 336-338. https://doi.org/10.4323/rjlm.2021.336

APA Citation styleRolfes, C., Dettmeyer, R., & Hochscheid, C. (2021). NITROFURANTOIN-INDUCED LUNG DISEASE WITH FATAL OUTCOME: A CASE REPORT. Romanian Journal of Legal Medicine. 29(3), 336-338. https://doi.org/10.4323/rjlm.2021.336



Keywords


Lung diseasenitrofurantoin

Last updated on 2025-02-04 at 00:14