Journalartikel
Autorenliste: Karakizlis, Hristos; van Rosmalen, Marieke; Boide, Philipp; Askevold, Ingolf; Vogelaar, Serge; Lorf, Thomas; Berlakovich, Gabrielle; Nitschke, Martin; Padberg, Winfried; Weimer, Rolf
Jahr der Veröffentlichung: 2022
Zeitschrift: Clinical Transplantation
Bandnummer: 36
Heftnummer: 3
ISSN: 0902-0063
eISSN: 1399-0012
Open Access Status: Green
DOI Link: https://doi.org/10.1111/ctr.14554
Verlag: Wiley
Abstract:
Background The shortage of organs for transplantation remains a global problem. The retransplantation of a previously transplanted kidney might be a possibility to expand the pool of donors. We provide our experience with the successful reuse of transplanted kidneys in the Eurotransplant region. Methods A query in the Eurotransplant database was performed between January 1, 1995 and December 31, 2015, to find kidney donors who themselves had previously received a kidney graft. Results Nine out of a total of 68,554 allocated kidneys had previously been transplanted. Four of these kidneys were transplanted once again. The mean interval between the first transplant and retransplantation was 1689 +/- 1682 days (SD; range 55-5,333 days). At the time of the first transplantation the mean serum creatinine of the donors was 1.0 mg/dl (.6-1.3 mg/dl) and at the second transplantation 1.4 mg/dl (.8-1.5 mg/dl). The mean graft survival in the first recipient was 50 months (2-110 months) and in the second recipient 111 months (40-215 months). Conclusion Transplantation of a previously transplanted kidney may successfully be performed with well-preserved graft function and long-term graft survival, even if the first transplantation was performed a long time ago. Such organs should be considered even for younger recipients in carefully selected cases.
Zitierstile
Harvard-Zitierstil: Karakizlis, H., van Rosmalen, M., Boide, P., Askevold, I., Vogelaar, S., Lorf, T., et al. (2022) Retransplanting a previously transplanted kidney: A safe strategy in times of organ shortage?, Clinical Transplantation, 36(3), Article e14554. https://doi.org/10.1111/ctr.14554
APA-Zitierstil: Karakizlis, H., van Rosmalen, M., Boide, P., Askevold, I., Vogelaar, S., Lorf, T., Berlakovich, G., Nitschke, M., Padberg, W., & Weimer, R. (2022). Retransplanting a previously transplanted kidney: A safe strategy in times of organ shortage?. Clinical Transplantation. 36(3), Article e14554. https://doi.org/10.1111/ctr.14554
Schlagwörter
DONORS; Graft survival; kidney injury; organ shortage; RECIPIENTS; retransplantation; REUSE; SURVIVAL BENEFIT
