Journal article

Publication year: 2021

Pages: 42-49

Journal: European Journal of Internal Medicine

Volume number: 93

ISSN: 0953-6205

eISSN: 1879-0828

DOI Link: https://doi.org/10.1016/j.ejim.2021.07.005

Publisher: Elsevier

Abstract: 
Introduction: Aim of this study was to prospectively assess the effects of multimodal rheumatologic complex treatment (MRCT), a special concept of in-patient physical treatment (PT) for treating spondyloarthritis (SpA), namely radiographic (r-) and non-radiographic (nr-) axial (ax-) SpA and psoriatic arthritis (PsA). Methods: r-, nr-axSpA and PsA patients receiving a 16-day MRCT were eligible. MRCT was delivered to participants over 64 PT sessions of various modalities with a minimum of 1,400 min of treatment. Primary outcome was a change in pain levels measured on a numeric rating scale (NRS, 0 - 10) between baseline and discharge. Secondary outcomes were assessments of i) disease activity ii) functional disabilities iii) serum cytokine levels iv) analgesic usage v) patient global health assessment and patients' satisfaction with their therapeutic response to MRCT from baseline to discharge and over a 12-week follow-up. Results: 50 patients completed the study and were analysed. Pain levels were improved significantly (p < 0.001, 95% confidence interval -2.25 to -0.8,). Further analyses revealed no influencing factors or relevant inter-group differences. Positive effects of MRCT lasted up to 12 weeks after discharge. Analgesic usage was reduced compared to baseline. Patient global health assessment continued to be improved throughout the whole followup. No MRCT-related harms were recorded. Conclusion: MRCT as a multimodal treatment concept with a strong emphasis on PT reduces pain in SpA meaningfully and facilitates reduced analgesic usage.

Harvard Citation style: Klemm, P., Preusler, P., Hudowenz, O., Asendorf, T., Mueller-Ladner, U., Neumann, E., et al. (2021) Multimodal rheumatologic complex treatment in patients with spondyloarthritis-a prospective study, European journal of internal medicine, 93, pp. 42-49. https://doi.org/10.1016/j.ejim.2021.07.005

APA Citation style: Klemm, P., Preusler, P., Hudowenz, O., Asendorf, T., Mueller-Ladner, U., Neumann, E., Lange, U., & Tarner, I. (2021). Multimodal rheumatologic complex treatment in patients with spondyloarthritis-a prospective study. European journal of internal medicine. 93, 42-49. https://doi.org/10.1016/j.ejim.2021.07.005