Journal article

Publication year: 2021

Pages: 961-965

Journal: Journal of Veterinary Diagnostic Investigation

Volume number: 33

Issue number: 5

ISSN: 1040-6387

eISSN: 1943-4936

Open access status: Green

DOI Link: https://doi.org/10.1177/10406387211020721

Publisher: SAGE Publications

Abstract: 
Atypical myopathy (AM) is an acute seasonal rhabdomyolysis seen primarily in equids, caused by the ingestion of sycamore maple samaras containing hypoglycin A (HGA) and methylenecyclopropyl-glycine (MCPG). Toxic metabolites inhibit acyl-CoA dehydrogenases and enoyl-CoA hydratases, causing selective hyaline degeneration of type I muscle fibers. Two zoo-kept Bactrian camels (Camelus bactrianus) with a fatal course of AM had sudden onset of muscle pain and weakness, recumbency, and dysphagia, accompanied by increased serum creatine kinase activity and detection in serum of HGA, MCPG, and metabolites. Medical treatment was ineffective. At postmortem examination, sycamore maple tree material was found within the first gastric compartment of the 2-y-old gelding. Although musculature was macroscopically normal, histologically, monophasic hyaline degeneration was marked within type I fibers of intercostal and hypoglossal muscles of the gelding, and in neck, tongue, and masticatory muscles of the cow. The ingestion of sycamore maple material can cause AM in Bactrian camels, and trees of the Sapindaceae family should be avoided in enclosures.

Harvard Citation style: Hirz, M., Gregersen, H., Sander, J., Votion, D., Schaenzer, A., Koehler, K., et al. (2021) Atypical myopathy in 2 Bactrian camels, Journal of Veterinary Diagnostic Investigation, 33(5), Article 10406387211020721. pp. 961-965. https://doi.org/10.1177/10406387211020721

APA Citation style: Hirz, M., Gregersen, H., Sander, J., Votion, D., Schaenzer, A., Koehler, K., & Herden, C. (2021). Atypical myopathy in 2 Bactrian camels. Journal of Veterinary Diagnostic Investigation. 33(5), Article 10406387211020721, 961-965. https://doi.org/10.1177/10406387211020721