Journalartikel

Jahr der Veröffentlichung: 2020

Zeitschrift: Frontiers in Oncology

Bandnummer: 10

ISSN: 2234-943X

Open Access Status: Gold

DOI Link: https://doi.org/10.3389/fonc.2020.00477

Verlag: Frontiers Media

Abstract: 
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults. We present a case of a 42-year-old male patient presenting with headache and vomiting. Imaging demonstrated obstructive hydrocephalus and a ring-enhancing lesion in the right posterior thalamus. After endoscopic third ventriculostomy and stereotactic biopsy, the histopathologic diagnosis of a malignant glioma was confirmed by DNA methylation array as GBM isocitrate dehydrogenase wild type. The patient was treated with combined treatment of chemoradiation with temozolomide (TMZ) including proton boost, TMZ maintenance, and tumor-treating fields. In this case report, complete radiological response was observed 1 year after the end of radiation therapy.

Harvard-Zitierstil: Stein, M., Dohmen, H., Woelk, B., Eberle, F., Kolodziej, M., Acker, T., et al. (2020) Case Report of Complete Radiological Response of a Thalamic Glioblastoma After Treatment With Proton Therapy Followed by Temozolomide and Tumor-Treating Fields, Frontiers in Oncology, 10, Article 477. https://doi.org/10.3389/fonc.2020.00477

APA-Zitierstil: Stein, M., Dohmen, H., Woelk, B., Eberle, F., Kolodziej, M., Acker, T., Uhl, E., & Jensen, A. (2020). Case Report of Complete Radiological Response of a Thalamic Glioblastoma After Treatment With Proton Therapy Followed by Temozolomide and Tumor-Treating Fields. Frontiers in Oncology. 10, Article 477. https://doi.org/10.3389/fonc.2020.00477