Journal article

Publication year: 2022

Pages: 144-147

Journal: Wiener Medizinische Wochenschrift

Volume number: 172

Issue number: 5-6

ISSN: 0043-5341

eISSN: 1563-258X

Open access status: Hybrid

DOI Link: https://doi.org/10.1007/s10354-020-00795-6

Publisher: Springer

Abstract: 
Case presentation We report a case of severe glycogenic hepatopathy in a 17-year-old boy with poorly controlled type 1 diabetes. On presentation, major findings included unexplained pronounced hepatomegaly and increased liver enzymes, ferritin, and triglycerides. Histology and electron microscopy evaluation showed severe glycogen storage, steatosis, and signs of fibrosis, resembling the histomorphological findings of Mauriac syndrome. After information about the nature of the disease and intensification of insulin therapy with insulin pump, liver enzymes, ferritin, and triglycerides normalized within 1 month. Conclusion Glycogenic hepatopathy is a rare but important potential complication in poorly controlled juvenile diabetic patients. With improved metabolic control, it is fully reversible.

Harvard Citation style: de Laffolie, J., Kamrath, C., Burchert, D., Boettcher, C., Wudy, S. and Zimmer, K. (2022) Reversible severe glycogenic hepatopathy in type 1 diabetes, Wiener Medizinische Wochenschrift, 172(5-6), pp. 144-147. https://doi.org/10.1007/s10354-020-00795-6

APA Citation style: de Laffolie, J., Kamrath, C., Burchert, D., Boettcher, C., Wudy, S., & Zimmer, K. (2022). Reversible severe glycogenic hepatopathy in type 1 diabetes. Wiener Medizinische Wochenschrift. 172(5-6), 144-147. https://doi.org/10.1007/s10354-020-00795-6