Journal article

Heterotopic Ossification of the Vascular Pedicle after Maxillofacial Reconstructive Surgery Using Fibular Free Flap: Introducing New Classification and Retrospective Analysis


Authors listKnitschke, Michael; Siu, Kelly; Baecker, Christina; Attia, Sameh; Howaldt, Hans-Peter; Boettger, Sebastian

Publication year2021

JournalJournal of Clinical Medicine

Volume number10

Issue number1

eISSN2077-0383

Open access statusGold

DOI Linkhttps://doi.org/10.3390/jcm10010109

PublisherMDPI


Abstract
Heterotopic ossification (HO) is one of the described phenomena after maxillofacial reconstructive surgery using fibular free flap (FFF) at the reception-site. The aim of this study was to determine the radiological incidence and form of HO along the fibular vascular pedicle as well as the rate of clinical symptoms if present. CT-scans of 102 patients who underwent jaw reconstructive surgery by using FFF from January 2005 to December 2019 were evaluated concerning the presence of HO. Subsequently, the patient files were evaluated to identify the cases with clinical signs and complications related to the presence of HO. A radiological classification of four different HO types was developed. Out of 102 patients, 29 (28.43%) presented radiological findings of HO. Clinical symptoms were recorded in 10 cases (9.8%) (dysphagia (n = 5), trismus (n = 3), bony masses (n = 2)) and from these only five (4.9%) needed surgical removal of calcified structures. HO occurs significantly in younger patients (mean 52.3 year). In maxillary reconstructions, HO was radiologically visible six months earlier than after mandibular reconstruction. Furthermore, HO is observed after every third maxilla and every fourth mandible reconstruction. This study developed for the first time a classification of four distinct HO patterns. HO types 1 and 2 were mostly observed after mandible reconstruction and type 4 predominantly after maxilla reconstruction.



Citation Styles

Harvard Citation styleKnitschke, M., Siu, K., Baecker, C., Attia, S., Howaldt, H. and Boettger, S. (2021) Heterotopic Ossification of the Vascular Pedicle after Maxillofacial Reconstructive Surgery Using Fibular Free Flap: Introducing New Classification and Retrospective Analysis, Journal of Clinical Medicine, 10(1), Article 109. https://doi.org/10.3390/jcm10010109

APA Citation styleKnitschke, M., Siu, K., Baecker, C., Attia, S., Howaldt, H., & Boettger, S. (2021). Heterotopic Ossification of the Vascular Pedicle after Maxillofacial Reconstructive Surgery Using Fibular Free Flap: Introducing New Classification and Retrospective Analysis. Journal of Clinical Medicine. 10(1), Article 109. https://doi.org/10.3390/jcm10010109



Keywords


ASSISTED MANDIBULAR RECONSTRUCTIONFFFfibular free flapheterotopic ossificationmicrosurgeryMICROVASCULAR RECONSTRUCTIONOSTEOSEPTOCUTANEOUS FLAPPERIOSTEAL OSSIFICATIONPLATESRARE PHENOMENONreconstructive surgerySKIN PADDLE

Last updated on 2025-10-06 at 11:20