Journal article
Authors list: Behr, Jurgen; Guenther, Andreas; Bonella, Francesco; Dinkel, Julien; Fink, Ludger; Geiser, Thomas; Geissler, Klaus; Glaser, Sven; Handzhiev, Sabin; Jonigk, Danny; Koschel, Dirk; Kreuter, Michael; Leuschner, Gabriela; Markart, Philipp; Prasse, Antje; Schoenfeld, Nicolas; Schupp, Jonas Christian; Sitter, Helmut; Muller-Quernheim, Joachim; Costabel, Ulrich
Publication year: 2021
Pages: 238-270
Journal: Respiration
Volume number: 100
Issue number: 3
ISSN: 0025-7931
eISSN: 1423-0356
Open access status: Bronze
DOI Link: https://doi.org/10.1159/000512315
Publisher: Karger Publishers
Abstract:
Idiopathic pulmonary fibrosis (IPF) is a severe and often fatal disease. Diagnosis of IPF requires considerable expertise and experience. Since the publication of the international IPF guideline in the year 2011 and the update 2018 several studies and technical advances have occurred, which made a new assessment of the diagnostic process mandatory. The goal of this guideline is to foster early, confident, and effective diagnosis of IPF. The guideline focusses on the typical clinical context of an IPF patient and provides tools to exclude known causes of interstitial lung disease including standardized questionnaires, serologic testing, and cellular analysis of bronchoalveolar lavage. High-resolution computed tomography remains crucial in the diagnostic workup. If it is necessary to obtain specimens for histology, transbronchial lung cryobiopsy is the primary approach, while surgical lung biopsy is reserved for patients who are fit for it and in whom a bronchoscopic diagnosis did not provide the information needed. After all, IPF is a diagnosis of exclusion and multidisciplinary discussion remains the golden standard of diagnosis.
Citation Styles
Harvard Citation style: Behr, J., Guenther, A., Bonella, F., Dinkel, J., Fink, L., Geiser, T., et al. (2021) S2K Guideline for Diagnosis of Idiopathic Pulmonary Fibrosis, Respiration, 100(3), pp. 238-270. https://doi.org/10.1159/000512315
APA Citation style: Behr, J., Guenther, A., Bonella, F., Dinkel, J., Fink, L., Geiser, T., Geissler, K., Glaser, S., Handzhiev, S., Jonigk, D., Koschel, D., Kreuter, M., Leuschner, G., Markart, P., Prasse, A., Schoenfeld, N., Schupp, J., Sitter, H., Muller-Quernheim, J., ...Costabel, U. (2021). S2K Guideline for Diagnosis of Idiopathic Pulmonary Fibrosis. Respiration. 100(3), 238-270. https://doi.org/10.1159/000512315
Keywords
ACUTE EXACERBATION; BRONCHOALVEOLAR LAVAGE; CLINICAL-USEFULNESS; FLEISCHNER-SOCIETY; GUIDELINE; High-resolution computed tomography; Idiopathic pulmonary fibrosis; INTERSTITIAL LUNG-DISEASE; OCCUPATIONAL-EXPOSURE; RESOLUTION COMPUTED-TOMOGRAPHY; SURGICAL BIOPSY; TRANSBRONCHIAL CRYOBIOPSY; VIDEO-ASSISTED THORACOSCOPY
