Journal article
Authors list: Kulich, Ivan; Vogler, Frank; Bleckmann, Andrea; Cyprys, Philipp; Lindemeier, Maria; Fuchs, Ingrid; Krassini, Laura; Schubert, Thomas; Steinbrenner, Jens; Beynon, Jim; Falter-Braun, Pascal; Laengst, Gernot; Dresselhaus, Thomas; Sprunck, Stefanie
Publication year: 2020
Pages: 1275-127+
Journal: Nature Plants
Volume number: 6
Issue number: 10
ISSN: 2055-026X
eISSN: 2055-0278
DOI Link: https://doi.org/10.1038/s41477-020-00781-1
Publisher: Nature Research
Polar growth requires the precise tuning of Rho GTPase signalling at distinct plasma membrane domains. The activity of Rho of plant (ROP) GTPases is regulated by the opposing action of guanine nucleotide-exchange factors (GEFs) and GTPase-activating proteins (GAPs). Whereas plant-specific ROPGEFs have been shown to be embedded in higher-level regulatory mechanisms involving membrane-bound receptor-like kinases, the regulation of GAPs has remained enigmatic. Here, we show that threeArabidopsisARMADILLO REPEAT ONLY (ARO) proteins are essential for the stabilization of growth sites in root hair cells and trichomes. AROs interact with ROP1 enhancer GAPs (RENGAPs) and bind to the plasma membrane via a conserved polybasic region at the ARO amino terminus. The ectopic spreading of ROP2 inaro2/3/4mutant root hair cells and the preferential interaction of AROs with active ROPs and anionic phospholipids suggests that AROs recruit RENGAPs into complexes with ROPs to confine ROP signalling to distinct membrane regions. Cell polarity that requires asymmetrical distribution of cellular components is important for plant growth and development. Here the authors identify a group of ARMADILLO domain proteins that collectively act in the polarized cell expansion of tip-growing cells by recruiting Rho of plant 1 (ROP1) enhancer GTPase-activating proteins and therefore ROP signalling to distinct plasma membrane sites.
Abstract:
Citation Styles
Harvard Citation style: Kulich, I., Vogler, F., Bleckmann, A., Cyprys, P., Lindemeier, M., Fuchs, I., et al. (2020) ARMADILLO REPEAT ONLY proteins confine Rho GTPase signalling to polar growth sites, Nature Plants, 6(10), pp. 1275-127+. https://doi.org/10.1038/s41477-020-00781-1
APA Citation style: Kulich, I., Vogler, F., Bleckmann, A., Cyprys, P., Lindemeier, M., Fuchs, I., Krassini, L., Schubert, T., Steinbrenner, J., Beynon, J., Falter-Braun, P., Laengst, G., Dresselhaus, T., & Sprunck, S. (2020). ARMADILLO REPEAT ONLY proteins confine Rho GTPase signalling to polar growth sites. Nature Plants. 6(10), 1275-127+. https://doi.org/10.1038/s41477-020-00781-1
Keywords
POLLEN GERMINATION; ROP GTPASES; TIP GROWTH