Journalartikel
Autorenliste: Koczulla, Rembert A.; Sczepanski, Bernd; Koteczki, Adam; Kuhnert, Stefan; Hecker, Matthias; Askevold, Ingolf; Schneider, Christian; Michel, Sebastian; Kneidinger, Nikolaus
Jahr der Veröffentlichung: 2020
Seiten: 2928-2932
Zeitschrift: American Journal of Transplantation
Bandnummer: 20
Heftnummer: 10
ISSN: 1600-6135
eISSN: 1600-6143
Open Access Status: Hybrid
DOI Link: https://doi.org/10.1111/ajt.15998
Verlag: Elsevier
Abstract:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has become a global health problem with pandemic character. Lung transplant recipients may be particularly at risk due to the high degree of immunosuppression and the lung being the organ primarily affected by COVID-19. We describe a 16-year-old male and a 64-year-old female recently lung transplanted patients with COVID-19 during inpatient rehabilitation. Both patients were receiving triple immunosuppressive therapy and had no signs of allograft dysfunction. Both patients had close contact with a person who developed COVID-19 and were tested positive for SARS-CoV-2. Subsequently, both patients underwent systematic screening and SARS-CoV-2 was ultimately detected. Although the 16-year-old boy was completely asymptomatic, the 64-year-old woman developed only mild COVID-19. Immunosuppressive therapy was unchanged and no experimental treatment was initiated. No signs of graft involvement or dysfunction were noticed. In conclusion, our report of patients with asymptomatic SARS-CoV-2 infection and mild COVID-19, respectively, may indicate that lung transplant recipients are not per se at risk for severe COVID-19. Further observations and controlled trials are urgently needed to study SARS-CoV-2 infection in lung transplant recipients.
Zitierstile
Harvard-Zitierstil: Koczulla, R., Sczepanski, B., Koteczki, A., Kuhnert, S., Hecker, M., Askevold, I., et al. (2020) SARS-CoV-2 infection in two patients following recent lung transplantation, American Journal of Transplantation, 20(10), pp. 2928-2932. https://doi.org/10.1111/ajt.15998
APA-Zitierstil: Koczulla, R., Sczepanski, B., Koteczki, A., Kuhnert, S., Hecker, M., Askevold, I., Schneider, C., Michel, S., & Kneidinger, N. (2020). SARS-CoV-2 infection in two patients following recent lung transplantation. American Journal of Transplantation. 20(10), 2928-2932. https://doi.org/10.1111/ajt.15998
Schlagwörter
Clinical research; infection and infectious agents - viral; infectious; Lung disease; LUNG TRANSPLANTATION; practice; pulmonology
