Journal article

Publication year: 2020

Pages: 428-439

Journal: Childhood Obesity

Volume number: 16

Issue number: 6

ISSN: 2153-2168

eISSN: 2153-2176

DOI Link: https://doi.org/10.1089/chi.2019.0307

Publisher: Mary Ann Liebert

Abstract: 
Background:Increased central (or abdominal) fat mass has been associated with cardiometabolic risk factors such as high low-density lipoproteins (LDL)-cholesterol or triglycerides (TG) concentration in children. Objectives:To generate pediatric reference centiles for trunk/leg fat mass ratio (T2L) (assessed by dual-energy X-ray absorptiometry [DXA]) and to evaluate the association of LDL-cholesterol and TG concentrations with T2L in children and adolescents.Methods:Data of the National Health and Nutrition Examination Survey (1999-2004) were used to determine total and regional fat mass by DXA of the participants (aged 8-19 years) who had also an examination of LDL-cholesterol and TG concentrations. Fat mass was assessed by DXA-determined fat mass index (FMI). Central fat mass was quantified by T2L. Results:The DXA results of 6538 children and adolescents (2629 females) were used to generate reference centiles for T2L. In girls, T2L was significantly associated with high LDL-cholesterol and TG concentration (odds ratio [OR] adjusted to FMI 1.69), (95% confidence interval [CI] 1.20-2.40), and 1.45 (95% CI 1.11-1.91,p = 0.003 andp = 0.008). In boys, T2L was significantly associated only with high TG concentration (OR adjusted to FMI 1.81 [95% CI 1.52-2.19,p < 0.001]). Conclusions:A central fat distribution seemed to be an independent risk factor for high TG concentrations in children and for high LDL-cholesterol only in girls. The first ethnicity-specific, pediatric reference centiles for T2L were presented.

Harvard Citation style: Duran, I., Martakis, K., Alberg, E., Jackels, M., Ewert, K. and Schoenau, E. (2020) Association of Trunk/Leg Fat Mass Ratio with Low-Density Lipoproteins-Cholesterol and Triglycerides Concentration in Children and Adolescents: A Cross-Sectional, Retrospective Study, Childhood Obesity, 16(6), pp. 428-439. https://doi.org/10.1089/chi.2019.0307

APA Citation style: Duran, I., Martakis, K., Alberg, E., Jackels, M., Ewert, K., & Schoenau, E. (2020). Association of Trunk/Leg Fat Mass Ratio with Low-Density Lipoproteins-Cholesterol and Triglycerides Concentration in Children and Adolescents: A Cross-Sectional, Retrospective Study. Childhood Obesity. 16(6), 428-439. https://doi.org/10.1089/chi.2019.0307