Journal article

Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension


Authors listRichter, Manuel J.; Harutyunova, Satenik; Bollmann, Tom; Classen, Simon; Fuge, Jan; Gall, Henning; Gerhardt, Felix; Ghofrani, Hossein A.; Gunkel, Hartmut; Gruenig, Ekkehard; Halank, Michael; Heine, Alexander; Klose, Hans; Lange, Tobias J.; Neurohr, Claus; Nickolaus, Kai; Opitz, Christian F.; Rosenkranz, Stephan; Seyfarth, Hans-Juergen; Tello, Khodr; Ewert, Ralf; Olsson, Karen M.

Publication year2020

JournalPulmonary Circulation

Volume number10

Issue number1

ISSN2045-8932

eISSN2045-8940

Open access statusGold

DOI Linkhttps://doi.org/10.1177/2045894020910136

PublisherWiley


Abstract
Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro (R) pump (approved in Europe) has a fixed flow rate. Based on 126 pumps and 2853 refills, we retrospectively analyzed the actual flow rate from 09/2010 to 09/2018. A relevant flow rate variance is evident after three years; therefore, flow rate monitoring and dose adjustment are mandatory.



Citation Styles

Harvard Citation styleRichter, M., Harutyunova, S., Bollmann, T., Classen, S., Fuge, J., Gall, H., et al. (2020) Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension, Pulmonary Circulation, 10(1), Article 2045894020910136. https://doi.org/10.1177/2045894020910136

APA Citation styleRichter, M., Harutyunova, S., Bollmann, T., Classen, S., Fuge, J., Gall, H., Gerhardt, F., Ghofrani, H., Gunkel, H., Gruenig, E., Halank, M., Heine, A., Klose, H., Lange, T., Neurohr, C., Nickolaus, K., Opitz, C., Rosenkranz, S., Seyfarth, H., ...Olsson, K. (2020). Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension. Pulmonary Circulation. 10(1), Article 2045894020910136. https://doi.org/10.1177/2045894020910136



Keywords


implantable infusion pumpprostanoidPulmonary hypertension

Last updated on 2025-10-06 at 11:10