Journal article

A WAO - ARIA - GA2LEN consensus document on molecular-based allergy diagnosis (PAMD@): Update 2020


Authors listAnsotegui, Ignacio J.; Melioli, Giovanni; Canonica, Giorgio Walter; Maximiliano Gomez, R.; Jensen-Jarolim, Erika; Ebisawa, Motohiro; Luengo, Olga; Caraballo, Luis; Passalacqua, Giovanni; Poulsen, Lars K.; Savi, Eleonora; Zuberbier, Torsten; Villa, Elisa; Oppenheimer, John; Asero, Riccardo; Bernstein, Jonathan; Bousquet, Jean; Cardona, Victoria; Cox, Lindo; Demoly, Pascal; Ferreira, Fatima; Bianchi, Pedro Giavina; Gonzalez Diaz, Sandra; Jakob, Thilo; Tanno, Luciana Kase; Kleine-Tebbe, Jorg; Levin, Michael; Martin, Bryan; Matricardi, Paolo Maria; Monge Ortega, Olga Patricia; Almeida, Mario Morais; Nunes, Carlos; Ortega Martell, Jose Antonio; Renz, Harald; Rosario Filho, Nelson; Rouadi, Philip; Ruiba, Alessia; Sampson, Hugh; Sanchez Borges, Mario; Scala, Enrico; Schmid-Grendelmeier, Peter; Senna, Gian-Enrico; Carlos Sisul, Juan; Tang, Mimi L. K.; Valenta, Rudolf; van Hage, Marianne; Wong, Gary W. K.; Yanez, Anahi

Publication year2020

JournalWorld Allergy Organization Journal

Volume number13

Issue number2

ISSN1939-4551

DOI Linkhttps://doi.org/10.1016/j.waojou.2019.100091

PublisherElsevier


Abstract

Precision allergy molecular diagnostic applications (PAMD@) is increasingly entering routine care. Currently, more than 130 allergenic molecules from more than 50 allergy sources are commercially available for in vitro specific immunoglobulin E (sIgE) testing. Since the last publication of this consensus document, a great deal of new information has become available regarding this topic, with over 100 publications in the last year alone. It thus seems quite reasonable to publish an update. It is imperative that clinicians and immunologists specifically trained in allergology keep abreast of the new and rapidly evolving evidence available for PAMD@.

PAMD@ may initially appear complex to interpret; however, with increasing experience, the information gained provides relevant information for the allergist. This is especially true for food allergy, Hymenoptera allergy, and for the selection of allergen immunotherapy. Nevertheless, all sIgE tests, including PAMD@, should be evaluated within the framework of a patient's clinical history, because allergen sensitization does not necessarily imply clinical relevant allergies.




Citation Styles

Harvard Citation styleAnsotegui, I., Melioli, G., Canonica, G., Maximiliano Gomez, R., Jensen-Jarolim, E., Ebisawa, M., et al. (2020) A WAO - ARIA - GA2LEN consensus document on molecular-based allergy diagnosis (PAMD@): Update 2020, World Allergy Organization Journal, 13(2), Article 100091. https://doi.org/10.1016/j.waojou.2019.100091

APA Citation styleAnsotegui, I., Melioli, G., Canonica, G., Maximiliano Gomez, R., Jensen-Jarolim, E., Ebisawa, M., Luengo, O., Caraballo, L., Passalacqua, G., Poulsen, L., Savi, E., Zuberbier, T., Villa, E., Oppenheimer, J., Asero, R., Bernstein, J., Bousquet, J., Cardona, V., Cox, L., ...Yanez, A. (2020). A WAO - ARIA - GA2LEN consensus document on molecular-based allergy diagnosis (PAMD@): Update 2020. World Allergy Organization Journal. 13(2), Article 100091. https://doi.org/10.1016/j.waojou.2019.100091



Keywords


API M 10ARA H 2COMPONENT-RESOLVED DIAGNOSISCross reactivityDUST MITE ALLERGENHAZELNUT ALLERGYLIPID TRANSFER PROTEINM 2S ALBUMINMolecular allergyNEGATIVE SPECIFIC IGEPAMD@PanallergenPRU P 3SKIN PRICK TESTSSpecific IgE

Last updated on 2025-21-05 at 18:23