Journalartikel

Jahr der Veröffentlichung: 2020

Seiten: C9-C12

Zeitschrift: European journal of endocrinology

Bandnummer: 182

Heftnummer: 3

ISSN: 0804-4643

eISSN: 1479-683X

Open Access Status: Bronze

DOI Link: https://doi.org/10.1530/EJE-19-0995

Verlag: Oxford University Press

Abstract: 
Primary adrenal insufficiency (PAI) in children is mostly due to genetic defects. The understanding of the molecular genetics of the causes of adrenal insufficiency in the pediatric population has made significant progress during the last years. It has been shown that inherited PAI can lead to certain clinical manifestations and health problems in children beyond the adrenals. Organ dysfunctions associated with different forms of PAI in children include a wide range of organs such as gonads, brain, heart, bone, growth, bone marrow, kidney, skin, parathyroid, and thyroid. Diagnosing the correct genetic cause of PAI in children is therefore crucial to adequately control long-term treatment and follow-up in such patients.

Harvard-Zitierstil: Kamrath, C. (2020) Beyond the adrenals: Organ manifestations in inherited primary adrenal insufficiency in children, European journal of endocrinology, 182(3), pp. C9-C12. https://doi.org/10.1530/EJE-19-0995

APA-Zitierstil: Kamrath, C. (2020). Beyond the adrenals: Organ manifestations in inherited primary adrenal insufficiency in children. European journal of endocrinology. 182(3), C9-C12. https://doi.org/10.1530/EJE-19-0995