Journalartikel
Autorenliste: Foerster, Kai; Ertl-Wagner, Birgit; Ehrhardt, Harald; Busen, Hannah; Sass, Steffen; Pomschar, Andreas; Naehrlich, Lutz; Schulze, Andreas; Flemmer, Andreas W.; Huebener, Christoph; Eickelberg, Oliver; Theis, Fabian; Dietrich, Olaf; Hilgendorff, Anne
Jahr der Veröffentlichung: 2020
Seiten: 184-187
Zeitschrift: Thorax
Bandnummer: 75
Heftnummer: 2
ISSN: 0040-6376
eISSN: 1468-3296
Open Access Status: Green
DOI Link: https://doi.org/10.1136/thoraxjnl-2018-212384
Verlag: BMJ Publishing Group
Abstract:
We developed a MRI protocol using transverse (T2) and longitudinal (T1) mapping sequences to characterise lung structural changes in preterm infants with bronchopulmonary dysplasia (BPD). We prospectively enrolled 61 infants to perform 3-Tesla MRI of the lung in quiet sleep. Statistical analysis was performed using logistic Group Lasso regression and logistic regression. Increased lung T2 relaxation time and decreased lung T1 relaxation time indicated BPD yielding an area under the curve (AUC) of 0.80. Results were confirmed in an independent study cohort (AUC 0.75) and mirrored by lung function testing, indicating the high potential for MRI in future BPD diagnostics.
Zitierstile
Harvard-Zitierstil: Foerster, K., Ertl-Wagner, B., Ehrhardt, H., Busen, H., Sass, S., Pomschar, A., et al. (2020) Altered relaxation times in MRI indicate bronchopulmonary dysplasia, Thorax, 75(2), pp. 184-187. https://doi.org/10.1136/thoraxjnl-2018-212384
APA-Zitierstil: Foerster, K., Ertl-Wagner, B., Ehrhardt, H., Busen, H., Sass, S., Pomschar, A., Naehrlich, L., Schulze, A., Flemmer, A., Huebener, C., Eickelberg, O., Theis, F., Dietrich, O., & Hilgendorff, A. (2020). Altered relaxation times in MRI indicate bronchopulmonary dysplasia. Thorax. 75(2), 184-187. https://doi.org/10.1136/thoraxjnl-2018-212384
Schlagwörter
MAGNETIC-RESONANCE
